Polycystic Ovary Syndrome (PCOS) ICD-10-CM codes

Polycystic ovary syndrome has one code, E28.2, which sits in the endocrine chapter under ovarian dysfunction rather than in the genitourinary chapter. Polycystic ovaries, Stein-Leventhal syndrome, and PCOS all index to E28.2. The code carries no characters for laterality or severity.

E28.2 describes the syndrome, and its manifestations are coded in addition when the provider documents them and they are evaluated or treated: L68.0 hirsutism, N91.2 amenorrhea (or N91.1 secondary amenorrhea), N92.6 irregular menstruation, N97.0 female infertility associated with anovulation, E88.819 insulin resistance unspecified, and E66.- for obesity with the Z68 BMI code. Sequence E28.2 first when the visit is for management of PCOS itself, and the manifestation first when it is the reason for the encounter, such as an infertility work-up.

E28.1 (androgen excess) is used for hyperandrogenism when the provider has not diagnosed PCOS. Polycystic-appearing ovaries on ultrasound alone do not establish the syndrome; do not assign E28.2 from an imaging report without a provider diagnosis. Metformin used for PCOS is reported with Z79.84 only if the provider documents it as long-term therapy for the condition, and combined oral contraceptives used for cycle control are Z79.3.