Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
All CodesBillable Only
Browse by Section7 Sections
Internal Codes
PrevNext
  • D50—

    Iron deficiency anemia

  • D50.0—

    Iron deficiency anemia secondary to blood loss (chronic)

  • D50.1—

    Sideropenic dysphagia

  • D50.8—

    Other iron deficiency anemias

  • D50.9—

    Iron deficiency anemia, unspecified

  • D51—

    Vitamin B12 deficiency anemia

  • D51.0—

    Vitamin B12 deficiency anemia due to intrinsic factor deficiency

  • D51.1—

    Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria

  • D51.2—

    Transcobalamin II deficiency

  • D51.3—

    Other dietary vitamin B12 deficiency anemia

  • D51.8—

    Other vitamin B12 deficiency anemias

  • D51.9—

    Vitamin B12 deficiency anemia, unspecified

  • D52—

    Folate deficiency anemia

  • D52.0—

    Dietary folate deficiency anemia

  • D52.1—

    Drug-induced folate deficiency anemia

  • D52.8—

    Other folate deficiency anemias

  • D52.9—

    Folate deficiency anemia, unspecified

  • D53—

    Other nutritional anemias

  • D53.0—

    Protein deficiency anemia

  • D53.1—

    Other megaloblastic anemias, not elsewhere classified

  • D53.2—

    Scorbutic anemia

  • D53.8—

    Other specified nutritional anemias

  • D53.9—

    Nutritional anemia, unspecified

  • D55—

    Anemia due to enzyme disorders

  • D55.0—

    Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency

  • D55.1—

    Anemia due to other disorders of glutathione metabolism

  • D55.2—

    Anemia due to disorders of glycolytic enzymes

  • D55.21—

    Anemia due to pyruvate kinase deficiency

  • D55.29—

    Anemia due to other disorders of glycolytic enzymes

  • D55.3—

    Anemia due to disorders of nucleotide metabolism

  • D55.8—

    Other anemias due to enzyme disorders

  • D55.9—

    Anemia due to enzyme disorder, unspecified

  • D56—

    Thalassemia

  • D56.0—

    Alpha thalassemia

  • D56.1—

    Beta thalassemia

  • D56.2—

    Delta-beta thalassemia

  • D56.3—

    Thalassemia minor

  • D56.4—

    Hereditary persistence of fetal hemoglobin [HPFH]

  • D56.5—

    Hemoglobin E-beta thalassemia

  • D56.8—

    Other thalassemias

  • D56.9—

    Thalassemia, unspecified

  • D57—

    Sickle-cell disorders

  • D57.0—

    Hb-SS disease with crisis

  • D57.00—

    Hb-SS disease with crisis, unspecified

  • D57.01—

    Hb-SS disease with acute chest syndrome

  • D57.02—

    Hb-SS disease with splenic sequestration

  • D57.03—

    Hb-SS disease with cerebral vascular involvement

  • D57.04—

    Hb-SS disease with dactylitis

  • D57.09—

    Hb-SS disease with crisis with other specified complication

  • D57.1—

    Sickle-cell disease without crisis

Page 1 of 9Next