All ICD10 Codes
Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
All CodesBillable Only
Internal Codes
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  • D57.2|

    Sickle-cell/Hb-C disease

  • D57.20|

    Sickle-cell/Hb-C disease without crisis

  • D57.21|

    Sickle-cell/Hb-C disease with crisis

  • D57.211|

    Sickle-cell/Hb-C disease with acute chest syndrome

  • D57.212|

    Sickle-cell/Hb-C disease with splenic sequestration

  • D57.213|

    Sickle-cell/Hb-C disease with cerebral vascular involvement

  • D57.214|

    Sickle-cell/Hb-C disease with dactylitis

  • D57.218|

    Sickle-cell/Hb-C disease with crisis with other specified complication

  • D57.219|

    Sickle-cell/Hb-C disease with crisis, unspecified

  • D57.3|

    Sickle-cell trait

  • D57.4|

    Sickle-cell thalassemia

  • D57.40|

    Sickle-cell thalassemia without crisis

  • D57.41|

    Sickle-cell thalassemia, unspecified, with crisis

  • D57.411|

    Sickle-cell thalassemia, unspecified, with acute chest syndrome

  • D57.412|

    Sickle-cell thalassemia, unspecified, with splenic sequestration

  • D57.413|

    Sickle-cell thalassemia, unspecified, with cerebral vascular involvement

  • D57.414|

    Sickle-cell thalassemia, unspecified, with dactylitis

  • D57.418|

    Sickle-cell thalassemia, unspecified, with crisis with other specified complication

  • D57.419|

    Sickle-cell thalassemia, unspecified, with crisis

  • D57.42|

    Sickle-cell thalassemia beta zero without crisis

  • D57.43|

    Sickle-cell thalassemia beta zero with crisis

  • D57.431|

    Sickle-cell thalassemia beta zero with acute chest syndrome

  • D57.432|

    Sickle-cell thalassemia beta zero with splenic sequestration

  • D57.433|

    Sickle-cell thalassemia beta zero with cerebral vascular involvement

  • D57.434|

    Sickle-cell thalassemia beta zero with dactylitis

  • D57.438|

    Sickle-cell thalassemia beta zero with crisis with other specified complication

  • D57.439|

    Sickle-cell thalassemia beta zero with crisis, unspecified

  • D57.44|

    Sickle-cell thalassemia beta plus without crisis

  • D57.45|

    Sickle-cell thalassemia beta plus with crisis

  • D57.451|

    Sickle-cell thalassemia beta plus with acute chest syndrome

  • D57.452|

    Sickle-cell thalassemia beta plus with splenic sequestration

  • D57.453|

    Sickle-cell thalassemia beta plus with cerebral vascular involvement

  • D57.454|

    Sickle-cell thalassemia beta plus with dactylitis

  • D57.458|

    Sickle-cell thalassemia beta plus with crisis with other specified complication

  • D57.459|

    Sickle-cell thalassemia beta plus with crisis, unspecified

  • D57.8|

    Other sickle-cell disorders

  • D57.80|

    Other sickle-cell disorders without crisis

  • D57.81|

    Other sickle-cell disorders with crisis

  • D57.811|

    Other sickle-cell disorders with acute chest syndrome

  • D57.812|

    Other sickle-cell disorders with splenic sequestration

  • D57.813|

    Other sickle-cell disorders with cerebral vascular involvement

  • D57.814|

    Other sickle-cell disorders with dactylitis

  • D57.818|

    Other sickle-cell disorders with crisis with other specified complication

  • D57.819|

    Other sickle-cell disorders with crisis, unspecified

  • D58|

    Other hereditary hemolytic anemias

  • D58.0|

    Hereditary spherocytosis

  • D58.1|

    Hereditary elliptocytosis

  • D58.2|

    Other hemoglobinopathies

  • D58.8|

    Other specified hereditary hemolytic anemias

  • D58.9|

    Hereditary hemolytic anemia, unspecified

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