Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

All Codes Billable Only

Internal Codes

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D59|
Acquired hemolytic anemia
D59.0|
Drug-induced autoimmune hemolytic anemia
D59.1|
Other autoimmune hemolytic anemias
D59.10|
Autoimmune hemolytic anemia, unspecified
D59.11|
Warm autoimmune hemolytic anemia
D59.12|
Cold autoimmune hemolytic anemia
D59.13|
Mixed type autoimmune hemolytic anemia
D59.19|
Other autoimmune hemolytic anemia
D59.2|
Drug-induced nonautoimmune hemolytic anemia
D59.3|
Hemolytic-uremic syndrome
D59.30|
Hemolytic-uremic syndrome, unspecified
D59.31|
Infection-associated hemolytic-uremic syndrome
D59.32|
Hereditary hemolytic-uremic syndrome
D59.39|
Other hemolytic-uremic syndrome
D59.4|
Other nonautoimmune hemolytic anemias
D59.5|
Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
D59.6|
Hemoglobinuria due to hemolysis from other external causes
D59.8|
Other acquired hemolytic anemias
D59.9|
Acquired hemolytic anemia, unspecified
D60|
Acquired pure red cell aplasia [erythroblastopenia]
D60.0|
Chronic acquired pure red cell aplasia
D60.1|
Transient acquired pure red cell aplasia
D60.8|
Other acquired pure red cell aplasias
D60.9|
Acquired pure red cell aplasia, unspecified
D61|
Other aplastic anemias and other bone marrow failure syndromes
D61.0|
Constitutional aplastic anemia
D61.01|
Constitutional (pure) red blood cell aplasia
D61.02|
Shwachman-Diamond syndrome
D61.03|
Fanconi anemia
D61.09|
Other constitutional aplastic anemia
D61.1|
Drug-induced aplastic anemia
D61.2|
Aplastic anemia due to other external agents
D61.3|
Idiopathic aplastic anemia
D61.8|
Other specified aplastic anemias and other bone marrow failure syndromes
D61.81|
Pancytopenia
D61.810|
Antineoplastic chemotherapy induced pancytopenia
D61.811|
Other drug-induced pancytopenia
D61.818|
Other pancytopenia
D61.82|
Myelophthisis
D61.89|
Other specified aplastic anemias and other bone marrow failure syndromes
D61.9|
Aplastic anemia, unspecified
D62|
Acute posthemorrhagic anemia
D63|
Anemia in chronic diseases classified elsewhere
D63.0|
Anemia in neoplastic disease
D63.1|
Anemia in chronic kidney disease
D63.8|
Anemia in other chronic diseases classified elsewhere
D64|
Other anemias
D64.0|
Hereditary sideroblastic anemia
D64.1|
Secondary sideroblastic anemia due to disease
D64.2|
Secondary sideroblastic anemia due to drugs and toxins

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