Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • D59

    Acquired hemolytic anemia

  • D59.0

    Drug-induced autoimmune hemolytic anemia

  • D59.1

    Other autoimmune hemolytic anemias

  • D59.10

    Autoimmune hemolytic anemia, unspecified

  • D59.11

    Warm autoimmune hemolytic anemia

  • D59.12

    Cold autoimmune hemolytic anemia

  • D59.13

    Mixed type autoimmune hemolytic anemia

  • D59.19

    Other autoimmune hemolytic anemia

  • D59.2

    Drug-induced nonautoimmune hemolytic anemia

  • D59.3

    Hemolytic-uremic syndrome

  • D59.30

    Hemolytic-uremic syndrome, unspecified

  • D59.31

    Infection-associated hemolytic-uremic syndrome

  • D59.32

    Hereditary hemolytic-uremic syndrome

  • D59.39

    Other hemolytic-uremic syndrome

  • D59.4

    Other nonautoimmune hemolytic anemias

  • D59.5

    Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

  • D59.6

    Hemoglobinuria due to hemolysis from other external causes

  • D59.8

    Other acquired hemolytic anemias

  • D59.9

    Acquired hemolytic anemia, unspecified

  • D60

    Acquired pure red cell aplasia [erythroblastopenia]

  • D60.0

    Chronic acquired pure red cell aplasia

  • D60.1

    Transient acquired pure red cell aplasia

  • D60.8

    Other acquired pure red cell aplasias

  • D60.9

    Acquired pure red cell aplasia, unspecified

  • D61

    Other aplastic anemias and other bone marrow failure syndromes

  • D61.0

    Constitutional aplastic anemia

  • D61.01

    Constitutional (pure) red blood cell aplasia

  • D61.02

    Shwachman-Diamond syndrome

  • D61.03

    Fanconi anemia

  • D61.09

    Other constitutional aplastic anemia

  • D61.1

    Drug-induced aplastic anemia

  • D61.2

    Aplastic anemia due to other external agents

  • D61.3

    Idiopathic aplastic anemia

  • D61.8

    Other specified aplastic anemias and other bone marrow failure syndromes

  • D61.81

    Pancytopenia

  • D61.810

    Antineoplastic chemotherapy induced pancytopenia

  • D61.811

    Other drug-induced pancytopenia

  • D61.818

    Other pancytopenia

  • D61.82

    Myelophthisis

  • D61.89

    Other specified aplastic anemias and other bone marrow failure syndromes

  • D61.9

    Aplastic anemia, unspecified

  • D62

    Acute posthemorrhagic anemia

  • D63

    Anemia in chronic diseases classified elsewhere

  • D63.0

    Anemia in neoplastic disease

  • D63.1

    Anemia in chronic kidney disease

  • D63.8

    Anemia in other chronic diseases classified elsewhere

  • D64

    Other anemias

  • D64.0

    Hereditary sideroblastic anemia

  • D64.1

    Secondary sideroblastic anemia due to disease

  • D64.2

    Secondary sideroblastic anemia due to drugs and toxins

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