D80-D89Not billable, use a more specific code below
Certain disorders involving the immune mechanism (D80-D89)
Advertisements
Instructional notes
Includes: conditions that are coded here
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1: not coded here, use a different code
Excludes2: not included here, code separately if applicable
- human immunodeficiency virus [HIV] disease (B20)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
There are no chapter-specific rules for Chapter 3 yet, so the general rules in Section I.B apply.
All codes under D80-D89
D80-D89 can't be used on a claim. Pick a billable code below; grey headings group them.
- D80Immunodeficiency with predominantly antibody defects
- D80.0Hereditary hypogammaglobulinemia
- D80.1Nonfamilial hypogammaglobulinemia
- D80.2Selective deficiency of immunoglobulin A [IgA]
- D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4Selective deficiency of immunoglobulin M [IgM]
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7Transient hypogammaglobulinemia of infancy
- D80.8Other immunodeficiencies with predominantly antibody defects
- D80.9Immunodeficiency with predominantly antibody defects, unspecified
- D81Combined immunodeficiencies
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3Adenosine deaminase [ADA] deficiency
- D81.30Adenosine deaminase deficiency, unspecified
- D81.31Severe combined immunodeficiency due to adenosine deaminase deficiency
- D81.32Adenosine deaminase 2 deficiency
- D81.39Other adenosine deaminase deficiency
- D81.4Nezelof's syndrome
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.7Major histocompatibility complex class II deficiency
- D81.8Other combined immunodeficiencies
- D81.81Biotin-dependent carboxylase deficiency
- D81.810Biotinidase deficiency
- D81.818Other biotin-dependent carboxylase deficiency
- D81.819Biotin-dependent carboxylase deficiency, unspecified
- D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
- D81.89Other combined immunodeficiencies
- D81.9Combined immunodeficiency, unspecified
- D82Immunodeficiency associated with other major defects
- D82.0Wiskott-Aldrich syndrome
- D82.1Di George's syndrome
- D82.2Immunodeficiency with short-limbed stature
- D82.3Immunodeficiency following hereditary defective response to Epstein-Barr virus
- D82.4Hyperimmunoglobulin E [IgE] syndrome
- D82.8Immunodeficiency associated with other specified major defects
- D82.9Immunodeficiency associated with major defect, unspecified
- D83Common variable immunodeficiency
- D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
- D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
- D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
- D83.8Other common variable immunodeficiencies
- D83.9Common variable immunodeficiency, unspecified
- D84Other immunodeficiencies
- D84.0Lymphocyte function antigen-1 [LFA-1] defect
- D84.1Defects in the complement system
- D84.8Other specified immunodeficiencies
- D84.81Immunodeficiency due to conditions classified elsewhere
- D84.82Immunodeficiency due to drugs and external causes
- D84.821Immunodeficiency due to drugs
- D84.822Immunodeficiency due to external causes
- D84.89Other immunodeficiencies
- D84.9Immunodeficiency, unspecified
- D86Sarcoidosis
- D86.0Sarcoidosis of lung
- D86.1Sarcoidosis of lymph nodes
- D86.2Sarcoidosis of lung with sarcoidosis of lymph nodes
- D86.3Sarcoidosis of skin
- D86.8Sarcoidosis of other sites
- D86.81Sarcoid meningitis
- D86.82Multiple cranial nerve palsies in sarcoidosis
- D86.83Sarcoid iridocyclitis
- D86.84Sarcoid pyelonephritis
- D86.85Sarcoid myocarditis
- D86.86Sarcoid arthropathy
- D86.87Sarcoid myositis
- D86.89Sarcoidosis of other sites
- D86.9Sarcoidosis, unspecified
- D89Other disorders involving the immune mechanism, not elsewhere classified
- D89.0Polyclonal hypergammaglobulinemia
- D89.1Cryoglobulinemia
- D89.2Hypergammaglobulinemia, unspecified
- D89.3Immune reconstitution syndrome
- D89.4Mast cell activation syndrome and related disorders
- D89.40Mast cell activation, unspecified
- D89.41Monoclonal mast cell activation syndrome
- D89.42Idiopathic mast cell activation syndrome
- D89.43Secondary mast cell activation
- D89.44Hereditary alpha tryptasemia
- D89.49Other mast cell activation disorder
- D89.8Other specified disorders involving the immune mechanism, not elsewhere classified
- D89.81Graft-versus-host disease
- D89.810Acute graft-versus-host disease
- D89.811Chronic graft-versus-host disease
- D89.812Acute on chronic graft-versus-host disease
- D89.813Graft-versus-host disease, unspecified
- D89.82Autoimmune lymphoproliferative syndrome [ALPS]
- D89.83Cytokine release syndrome
- D89.831Cytokine release syndrome, grade 1
- D89.832Cytokine release syndrome, grade 2
- D89.833Cytokine release syndrome, grade 3
- D89.834Cytokine release syndrome, grade 4
- D89.835Cytokine release syndrome, grade 5
- D89.839Cytokine release syndrome, grade unspecified
- D89.84IgG4-related disease
- D89.89Other specified disorders involving the immune mechanism, not elsewhere classified
- D89.9Disorder involving the immune mechanism, unspecified
D80-D89 MS-DRGs
This code does not group to an MS-DRG as a principal diagnosis.
Other codes that refer to D80-D89
Notes on these codes point to D80-D89.
- D72 Excludes1: immunity disorders (D80-D89)