All ICD10 Codes

D89

Non-Billable
ChapterD50–D89
Rankcategory
Official Description

Other disorders involving the immune mechanism, not elsewhere classified

Use a more specific code (5 billable, 2 non-billable)
D89.0Polyclonal hypergammaglobulinemiaD89.1CryoglobulinemiaD89.2Hypergammaglobulinemia, unspecifiedD89.3Immune reconstitution syndromeD89.4Mast cell activation syndrome and related disordershas subcodesD89.8Other specified disorders involving the immune mechanism, not elsewhere classifiedhas subcodesD89.9Disorder involving the immune mechanism, unspecified
Metadata & Insights
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

D80-D89 Parent Instructions

Includes
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis
Excludes1(Not coded here. Use a different code.)
  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)
  • human immunodeficiency virus [HIV] disease (B20)

Instructional Notes

Excludes1(Not coded here. Use a different code.)
  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)
Excludes2(Not included here. Code separately if applicable.)
  • transplant failure and rejection (T86.-)

Clinical Hierarchy

BillableHas subcodes
CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D80-D89Certain disorders involving the immune mechanism (D80-D89)
D89Other disorders involving the immune mechanism, not elsewhere classifiedNot billable
D89.0Polyclonal hypergammaglobulinemiaBillable
D89.1CryoglobulinemiaBillable
D89.2Hypergammaglobulinemia, unspecifiedBillable
D89.3Immune reconstitution syndromeBillable
D89.4Mast cell activation syndrome and related disordersSubcodes
D89.8Other specified disorders involving the immune mechanism, not elsewhere classifiedSubcodes
D89.9Disorder involving the immune mechanism, unspecifiedBillable

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D89:

blockD80-D89
Certain disorders involving the immune mechanism (D80-D89)
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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