All ICD10 Codes
D89Not billable, use a more specific code below

Other disorders involving the immune mechanism, not elsewhere classified

In Certain disorders involving the immune mechanism (D80-D89), chapter 3: Diseases of the Blood and Blood-Forming Organs

24 billable codes under D89: 7 are a CC; 5 map to HCC 454 (Stem Cell, Including Bone Marrow, Transplant Status/Complications), HCC 115 (Specified Immunodeficiencies and White Blood Cell Disorders).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

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Instructional notes

Excludes1: not coded here, use a different code

  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2: not included here, code separately if applicable

  • transplant failure and rejection (T86.-)

Also applies, from Certain disorders involving the immune mechanism (D80-D89)

These notes sit on D80-D89 and apply to every code under it, including D89.

Includes: conditions that are coded here

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes1: not coded here, use a different code

  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2: not included here, code separately if applicable

  • human immunodeficiency virus [HIV] disease (B20)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

There are no chapter-specific rules for Chapter 3 yet, so the general rules in Section I.B apply.

Read Section I.C.3 (page 39)

All codes under D89

D89 can't be used on a claim. Pick a billable code below; grey headings group them.

D89 MS-DRGs

As the principal diagnosis, the billable codes under D89 group to these 18 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

Other codes that refer to D89

Notes on these codes point to D89.

  • D72 Excludes1: immunity disorders (D80-D89)
  • O99.1 Includes: Conditions in D65-D89
  • Z83.2 Includes: Conditions classifiable to D50-D89
  • Z86.2 Includes: Conditions classifiable to D50-D89

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.