DRG 815
Medical DRGReticuloendothelial and Immunity Disorders with CC
What is MS-DRG 815?
MS-DRG 815 is a Medical Medicare Severity Diagnosis Related Group under Major Diagnostic Category 16 (MDC 16) with a Complication or Comorbidity (CC). It maps to 137 ICD-10-CM diagnosis codes. For FY 2026 it carries a relative weight of 1.0140 with a geometric mean length of stay of 2.9 days and an arithmetic mean of 3.8 days. Hospitals use this grouping to determine reimbursement for inpatient stays under Medicare.
FY 2026 Payment Data
Official values from Table 5 of the FY 2026 IPPS Final Rule (CMS).
Related MS-DRGs in This Severity Group
The same clinical condition is split into separate DRGs by complication severity. MCC pays more than CC, which pays more than no CC/MCC.
Linked ICD-10-CM Diagnosis Mappings
- A18.2
Tuberculous peripheral lymphadenopathy
BillableChapter 1 - A18.85
Tuberculosis of spleen
BillableChapter 1 - A28.1
Cat-scratch disease
BillableChapter 1 - D15.0
Benign neoplasm of thymus
BillableChapter 2 - D18.1
Lymphangioma, any site
BillableChapter 2 - D36.0
Benign neoplasm of lymph nodes
BillableChapter 2 - D3A.091
Benign carcinoid tumor of the thymus
BillableChapter 2 - D47.2
Monoclonal gammopathy
BillableChapter 2 - D47.3
Essential (hemorrhagic) thrombocythemia
BillableChapter 2 - D47.4
Osteomyelofibrosis
BillableChapter 2 - D68.312
Antiphospholipid antibody with hemorrhagic disorder
BillableChapter 3 - D68.51
Activated protein C resistance
BillableChapter 3 - D68.52
Prothrombin gene mutation
BillableChapter 3 - D68.59
Other primary thrombophilia
BillableChapter 3 - D68.61
Antiphospholipid syndrome
BillableChapter 3 - D68.62
Lupus anticoagulant syndrome
BillableChapter 3 - D68.69
Other thrombophilia
BillableChapter 3 - D72.10
Eosinophilia, unspecified
BillableChapter 3 - D72.110
Idiopathic hypereosinophilic syndrome [IHES]
BillableChapter 3 - D72.111
Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
BillableChapter 3 - D72.118
Other hypereosinophilic syndrome
BillableChapter 3 - D72.119
Hypereosinophilic syndrome [HES], unspecified
BillableChapter 3 - D72.12
Drug rash with eosinophilia and systemic symptoms syndrome
BillableChapter 3 - D72.18
Eosinophilia in diseases classified elsewhere
BillableChapter 3 - D72.19
Other eosinophilia
BillableChapter 3 - D72.810
Lymphocytopenia
BillableChapter 3 - D72.818
Other decreased white blood cell count
BillableChapter 3 - D72.819
Decreased white blood cell count, unspecified
BillableChapter 3 - D72.820
Lymphocytosis (symptomatic)
BillableChapter 3 - D72.821
Monocytosis (symptomatic)
BillableChapter 3 - D72.822
Plasmacytosis
BillableChapter 3 - D72.823
Leukemoid reaction
BillableChapter 3 - D72.824
Basophilia
BillableChapter 3 - D72.825
Bandemia
BillableChapter 3 - D72.828
Other elevated white blood cell count
BillableChapter 3 - D72.829
Elevated white blood cell count, unspecified
BillableChapter 3 - D72.89
Other specified disorders of white blood cells
BillableChapter 3 - D72.9
Disorder of white blood cells, unspecified
BillableChapter 3 - D73.0
Hyposplenism
BillableChapter 3 - D73.1
Hypersplenism
BillableChapter 3 - D73.2
Chronic congestive splenomegaly
BillableChapter 3 - D73.3
Abscess of spleen
BillableChapter 3 - D73.4
Cyst of spleen
BillableChapter 3 - D73.5
Infarction of spleen
BillableChapter 3 - D73.81
Neutropenic splenomegaly
BillableChapter 3 - D73.89
Other diseases of spleen
BillableChapter 3 - D73.9
Disease of spleen, unspecified
BillableChapter 3 - D75.0
Familial erythrocytosis
BillableChapter 3 - D75.1
Secondary polycythemia
BillableChapter 3 - D75.838
Other thrombocytosis
BillableChapter 3 - D75.839
Thrombocytosis, unspecified
BillableChapter 3 - D75.89
Other specified diseases of blood and blood-forming organs
BillableChapter 3 - D75.9
Disease of blood and blood-forming organs, unspecified
BillableChapter 3 - D75.A
Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
BillableChapter 3 - D76.1
Hemophagocytic lymphohistiocytosis
BillableChapter 3 - D76.2
Hemophagocytic syndrome, infection-associated
BillableChapter 3 - D76.3
Other histiocytosis syndromes
BillableChapter 3 - D77
Other disorders of blood and blood-forming organs in diseases classified elsewhere
BillableChapter 3 - D80.0
Hereditary hypogammaglobulinemia
BillableChapter 3 - D80.1
Nonfamilial hypogammaglobulinemia
BillableChapter 3 - D80.2
Selective deficiency of immunoglobulin A [IgA]
BillableChapter 3 - D80.3
Selective deficiency of immunoglobulin G [IgG] subclasses
BillableChapter 3 - D80.4
Selective deficiency of immunoglobulin M [IgM]
BillableChapter 3 - D80.5
Immunodeficiency with increased immunoglobulin M [IgM]
BillableChapter 3 - D80.7
Transient hypogammaglobulinemia of infancy
BillableChapter 3 - D82.2
Immunodeficiency with short-limbed stature
BillableChapter 3 - D82.3
Immunodeficiency following hereditary defective response to Epstein-Barr virus
BillableChapter 3 - D82.4
Hyperimmunoglobulin E [IgE] syndrome
BillableChapter 3 - D82.8
Immunodeficiency associated with other specified major defects
BillableChapter 3 - D82.9
Immunodeficiency associated with major defect, unspecified
BillableChapter 3 - D83.0
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
BillableChapter 3 - D83.1
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
BillableChapter 3 - D83.2
Common variable immunodeficiency with autoantibodies to B- or T-cells
BillableChapter 3 - D83.8
Other common variable immunodeficiencies
BillableChapter 3 - D83.9
Common variable immunodeficiency, unspecified
BillableChapter 3 - D84.0
Lymphocyte function antigen-1 [LFA-1] defect
BillableChapter 3 - D84.81
Immunodeficiency due to conditions classified elsewhere
BillableChapter 3 - D84.821
Immunodeficiency due to drugs
BillableChapter 3 - D84.822
Immunodeficiency due to external causes
BillableChapter 3 - D84.89
Other immunodeficiencies
BillableChapter 3 - D84.9
Immunodeficiency, unspecified
BillableChapter 3 - D89.0
Polyclonal hypergammaglobulinemia
BillableChapter 3 - D89.2
Hypergammaglobulinemia, unspecified
BillableChapter 3 - D89.3
Immune reconstitution syndrome
BillableChapter 3 - D89.40
Mast cell activation, unspecified
BillableChapter 3 - D89.41
Monoclonal mast cell activation syndrome
BillableChapter 3 - D89.42
Idiopathic mast cell activation syndrome
BillableChapter 3 - D89.43
Secondary mast cell activation
BillableChapter 3 - D89.44
Hereditary alpha tryptasemia
BillableChapter 3 - D89.49
Other mast cell activation disorder
BillableChapter 3 - D89.831
Cytokine release syndrome, grade 1
BillableChapter 3 - D89.832
Cytokine release syndrome, grade 2
BillableChapter 3 - D89.833
Cytokine release syndrome, grade 3
BillableChapter 3 - D89.834
Cytokine release syndrome, grade 4
BillableChapter 3 - D89.835
Cytokine release syndrome, grade 5
BillableChapter 3 - D89.839
Cytokine release syndrome, grade unspecified
BillableChapter 3 - D89.84
IgG4-related disease
BillableChapter 3 - D89.89
Other specified disorders involving the immune mechanism, not elsewhere classified
BillableChapter 3 - D89.9
Disorder involving the immune mechanism, unspecified
BillableChapter 3 - E32.0
Persistent hyperplasia of thymus
BillableChapter 4 - E32.1
Abscess of thymus
BillableChapter 4 - E32.8
Other diseases of thymus
BillableChapter 4 - E32.9
Disease of thymus, unspecified
BillableChapter 4 - I88.1
Chronic lymphadenitis, except mesenteric
BillableChapter 9 - I88.8
Other nonspecific lymphadenitis
BillableChapter 9 - I88.9
Nonspecific lymphadenitis, unspecified
BillableChapter 9 - I89.8
Other specified noninfective disorders of lymphatic vessels and lymph nodes
BillableChapter 9 - I89.9
Noninfective disorder of lymphatic vessels and lymph nodes, unspecified
BillableChapter 9 - L04.0
Acute lymphadenitis of face, head and neck
BillableChapter 12 - L04.1
Acute lymphadenitis of trunk
BillableChapter 12 - L04.2
Acute lymphadenitis of upper limb
BillableChapter 12 - L04.3
Acute lymphadenitis of lower limb
BillableChapter 12 - L04.8
Acute lymphadenitis of other sites
BillableChapter 12 - L04.9
Acute lymphadenitis, unspecified
BillableChapter 12 - Q89.01
Asplenia (congenital)
BillableChapter 17 - Q89.09
Congenital malformations of spleen
BillableChapter 17 - R16.1
Splenomegaly, not elsewhere classified
BillableChapter 18 - R59.0
Localized enlarged lymph nodes
BillableChapter 18 - R59.1
Generalized enlarged lymph nodes
BillableChapter 18 - R59.9
Enlarged lymph nodes, unspecified
BillableChapter 18 - R75
Inconclusive laboratory evidence of human immunodeficiency virus [HIV]
BillableChapter 18 - R76.0
Raised antibody titer
BillableChapter 18 - R76.81
Abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis
BillableChapter 18 - R76.89
Other specified abnormal immunological findings in serum
BillableChapter 18 - R76.9
Abnormal immunological finding in serum, unspecified
BillableChapter 18 - S36.00XA
Unspecified injury of spleen, initial encounter
BillableChapter 19 - S36.020A
Minor contusion of spleen, initial encounter
BillableChapter 19 - S36.021A
Major contusion of spleen, initial encounter
BillableChapter 19 - S36.029A
Unspecified contusion of spleen, initial encounter
BillableChapter 19 - S36.030A
Superficial (capsular) laceration of spleen, initial encounter
BillableChapter 19 - S36.031A
Moderate laceration of spleen, initial encounter
BillableChapter 19 - S36.032A
Major laceration of spleen, initial encounter
BillableChapter 19 - S36.039A
Unspecified laceration of spleen, initial encounter
BillableChapter 19 - S36.09XA
Other injury of spleen, initial encounter
BillableChapter 19 - T80.82XA
Complication of immune effector cellular therapy, initial encounter
BillableChapter 19 - Z94.81
Bone marrow transplant status
BillableChapter 21 - Z94.84
Stem cells transplant status
BillableChapter 21
