Other immunodeficiencies
In Certain disorders involving the immune mechanism (D80-D89), chapter 3: Diseases of the Blood and Blood-Forming Organs
7 billable codes under D84: 5 are a CC; 1 map to HCC 115 (Specified Immunodeficiencies and White Blood Cell Disorders).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.
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Instructional notes
Also applies, from Certain disorders involving the immune mechanism (D80-D89)
These notes sit on D80-D89 and apply to every code under it, including D84.
Includes: conditions that are coded here
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1: not coded here, use a different code
Excludes2: not included here, code separately if applicable
- human immunodeficiency virus [HIV] disease (B20)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
There are no chapter-specific rules for Chapter 3 yet, so the general rules in Section I.B apply.
All codes under D84
D84 can't be used on a claim. Pick a billable code below; grey headings group them.
- D84.0Lymphocyte function antigen-1 [LFA-1] defect
- D84.1Defects in the complement system
- D84.8Other specified immunodeficiencies
- D84.81Immunodeficiency due to conditions classified elsewhere
- D84.82Immunodeficiency due to drugs and external causes
- D84.821Immunodeficiency due to drugs
- D84.822Immunodeficiency due to external causes
- D84.89Other immunodeficiencies
- D84.9Immunodeficiency, unspecified
D84 MS-DRGs
As the principal diagnosis, the billable codes under D84 group to MS-DRG 814, 815, 816, or 642 (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 814 Reticuloendothelial and Immunity Disorders with MCC (6 of 7 codes)
- DRG 815 Reticuloendothelial and Immunity Disorders with CC (6 of 7 codes)
- DRG 816 Reticuloendothelial and Immunity Disorders without CC/MCC (6 of 7 codes)
- DRG 642 Inborn and Other Disorders of Metabolism (1 of 7 codes)
Code history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
