Anemia due to enzyme disorders
In Hemolytic anemias (D55-D59), chapter 3: Diseases of the Blood and Blood-Forming Organs
7 billable codes under D55: none are a CC or MCC; none map to an HCC.
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Instructional notes
Excludes1: not coded here, use a different code
- drug-induced enzyme deficiency anemia (D59.2)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
There are no chapter-specific rules for Chapter 3 yet, so the general rules in Section I.B apply.
All codes under D55
D55 can't be used on a claim. Pick a billable code below; grey headings group them.
- D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
- D55.1Anemia due to other disorders of glutathione metabolism
- D55.2Anemia due to disorders of glycolytic enzymes
- D55.21Anemia due to pyruvate kinase deficiency
- D55.29Anemia due to other disorders of glycolytic enzymes
- D55.3Anemia due to disorders of nucleotide metabolism
- D55.8Other anemias due to enzyme disorders
- D55.9Anemia due to enzyme disorder, unspecified
D55 MS-DRGs
As the principal diagnosis, all 7 billable codes under D55 group to MS-DRG 811 or 812 (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
Other codes that refer to D55
Notes on these codes point to D55.
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read more about anemia on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.