Metastatic (Secondary) Cancer ICD-10-CM codes
ICD-10-CM codes for secondary malignant neoplasm of lymph nodes, respiratory and digestive organs, bone, brain, liver, and other sites, plus malignancy of unknown primary and disseminated cancer.
66 codes, 51 billable. FY2027, valid from October 1, 2026. In chapter 2: Neoplasms.
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How to code Metastatic (Secondary) Cancer
Secondary (metastatic) neoplasms are coded by the site of the metastasis: C77 for lymph nodes by region, C78 for respiratory and digestive organs (C78.0- lung, C78.2 pleura, C78.7 liver, C78.6 peritoneum), and C79 for all other sites (C79.31 brain, C79.51 bone, C79.52 bone marrow, C79.2 skin, C79.6- ovary, C79.7- adrenal). Sites with laterality carry it in the fifth character. Always code the primary site as well, and code each metastatic site separately.
Sequencing depends on the focus of the encounter. When treatment is directed at the primary, the primary is sequenced first and the secondary sites follow. When treatment is directed only at a metastatic site, for example radiation to bone metastases, the C79.51 code is principal and the primary is an additional code. If the primary has been previously excised and there is no evidence of it, use the Z85 history code for the primary together with the C77 to C79 code for the current metastasis.
Documentation language matters. Metastatic carcinoma of the lung means a secondary tumor in the lung (C78.0-); carcinoma metastatic from the lung means the lung is the primary (C34.-). When the primary cannot be determined, assign C80.1 (malignant neoplasm, primary site unspecified) with the secondary site codes. C80.0 (disseminated malignant neoplasm) is for widespread carcinomatosis where neither the primary nor specific secondary sites are documented, and C79.9 is a secondary neoplasm of unspecified site. These unspecified codes should be replaced as soon as the record identifies the sites.
Complications of metastatic disease are coded in addition: malignant pleural effusion J91.0, pathological fracture in neoplastic disease M84.5-, hypercalcemia E83.52, and anemia in neoplastic disease D63.0. Neoplasm-related pain is G89.3 and is sequenced first when the encounter is for pain control rather than treatment of the tumor.
All Metastatic (Secondary) Cancer codes
- C77Secondary and unspecified malignant neoplasm of lymph nodes
- C77.0Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck
- C77.1Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes
- C77.2Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes
- C77.3Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes
- C77.4Secondary and unspecified malignant neoplasm of inguinal and lower limb lymph nodes
- C77.5Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes
- C77.8Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions
- C77.9Secondary and unspecified malignant neoplasm of lymph node, unspecified
- C78Secondary malignant neoplasm of respiratory and digestive organs
- C78.0Secondary malignant neoplasm of lung
- C78.00Secondary malignant neoplasm of unspecified lung
- C78.01Secondary malignant neoplasm of right lung
- C78.02Secondary malignant neoplasm of left lung
- C78.1Secondary malignant neoplasm of mediastinum
- C78.2Secondary malignant neoplasm of pleura
- C78.3Secondary malignant neoplasm of other and unspecified respiratory organs
- C78.30Secondary malignant neoplasm of unspecified respiratory organ
- C78.31Secondary malignant neoplasm of larynx
- C78.32Secondary malignant neoplasm of pharynx
- C78.39Secondary malignant neoplasm of other respiratory organs
- C78.4Secondary malignant neoplasm of small intestine
- C78.5Secondary malignant neoplasm of large intestine and rectum
- C78.6Secondary malignant neoplasm of retroperitoneum and peritoneum
- C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
- C78.8Secondary malignant neoplasm of other and unspecified digestive organs
- C78.80Secondary malignant neoplasm of unspecified digestive organ
- C78.89Secondary malignant neoplasm of other digestive organs
- C79Secondary malignant neoplasm of other and unspecified sites
- C79.0Secondary malignant neoplasm of kidney and renal pelvis
- C79.00Secondary malignant neoplasm of unspecified kidney and renal pelvis
- C79.01Secondary malignant neoplasm of right kidney and renal pelvis
- C79.02Secondary malignant neoplasm of left kidney and renal pelvis
- C79.1Secondary malignant neoplasm of bladder and other and unspecified urinary organs
- C79.10Secondary malignant neoplasm of unspecified urinary organs
- C79.11Secondary malignant neoplasm of bladder
- C79.19Secondary malignant neoplasm of other urinary organs
- C79.2Secondary malignant neoplasm of skin
- C79.3Secondary malignant neoplasm of brain and cerebral meninges
- C79.31Secondary malignant neoplasm of brain
- C79.32Secondary malignant neoplasm of cerebral meninges
- C79.4Secondary malignant neoplasm of other and unspecified parts of nervous system
- C79.40Secondary malignant neoplasm of unspecified part of nervous system
- C79.49Secondary malignant neoplasm of other parts of nervous system
- C79.5Secondary malignant neoplasm of bone and bone marrow
- C79.51Secondary malignant neoplasm of bone
- C79.52Secondary malignant neoplasm of bone marrow
- C79.6Secondary malignant neoplasm of ovary
- C79.60Secondary malignant neoplasm of unspecified ovary
- C79.61Secondary malignant neoplasm of right ovary
- C79.62Secondary malignant neoplasm of left ovary
- C79.63Secondary malignant neoplasm of bilateral ovaries
- C79.7Secondary malignant neoplasm of adrenal gland
- C79.70Secondary malignant neoplasm of unspecified adrenal gland
- C79.71Secondary malignant neoplasm of right adrenal gland
- C79.72Secondary malignant neoplasm of left adrenal gland
- C79.8Secondary malignant neoplasm of other specified sites
- C79.81Secondary malignant neoplasm of breast
- C79.82Secondary malignant neoplasm of genital organs
- C79.83Secondary malignant neoplasm of oral cavity
- C79.89Secondary malignant neoplasm of other specified sites
- C79.9Secondary malignant neoplasm of unspecified site
- C80Malignant neoplasm without specification of site
- C80.0Disseminated malignant neoplasm, unspecified
- C80.1Malignant (primary) neoplasm, unspecified
- C80.2Malignant neoplasm associated with transplanted organ
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