Colorectal Cancer ICD-10-CM codes
ICD-10-CM codes for malignant neoplasm of the colon, rectosigmoid junction, rectum, and anus, plus liver metastasis, colon polyps, screening, and history codes.
27 codes, 25 billable. FY2027, valid from October 1, 2026. In chapter 2: Neoplasms.
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How to code Colorectal Cancer
Colon cancer is coded by segment with the fourth character of C18: C18.0 cecum, C18.1 appendix, C18.2 ascending colon, C18.3 hepatic flexure, C18.4 transverse colon, C18.5 splenic flexure, C18.6 descending colon, C18.7 sigmoid colon, C18.8 overlapping sites, and C18.9 colon unspecified. Cancer of the rectosigmoid junction is C19, rectum is C20, and anus and anal canal are C21.0 to C21.8. Colonoscopy and pathology reports almost always name the segment, so C18.9 should be uncommon.
Liver is the most frequent site of spread; code C78.7 in addition to the primary. Metastasis to regional lymph nodes is C77.2 (intra-abdominal) or C77.5 (intrapelvic). Sequencing follows the focus of care: the primary is first when it is being treated, the secondary site is first when treatment is directed only at the metastasis.
Benign polyps are not coded to chapter 2 malignancy categories: K63.5 is a polyp of colon and D12.- is a benign neoplasm (adenoma) by segment, with D12.6 for the colon unspecified. A polyp with high-grade dysplasia or carcinoma in situ is D01.- . Z86.0100 and Z86.0101 record a personal history of colon polyps (unspecified, or adenomatous and serrated) and support surveillance colonoscopy.
After curative resection with no evidence of disease and no ongoing treatment, report Z85.038 (history of malignant neoplasm of large intestine) or Z85.048 (rectum, rectosigmoid junction, and anus), plus Z90.49 if a portion of the bowel is absent. Z12.11 is the screening colonoscopy code for an average-risk patient; Z15.060 reports a confirmed genetic susceptibility such as Lynch syndrome.
All Colorectal Cancer codes
- C18Malignant neoplasm of colon
- C18.0Malignant neoplasm of cecum
- C18.1Malignant neoplasm of appendix
- C18.2Malignant neoplasm of ascending colon
- C18.3Malignant neoplasm of hepatic flexure
- C18.4Malignant neoplasm of transverse colon
- C18.5Malignant neoplasm of splenic flexure
- C18.6Malignant neoplasm of descending colon
- C18.7Malignant neoplasm of sigmoid colon
- C18.8Malignant neoplasm of overlapping sites of colon
- C18.9Malignant neoplasm of colon, unspecified
- C19Malignant neoplasm of rectosigmoid junction
- C20Malignant neoplasm of rectum
- C21Malignant neoplasm of anus and anal canal
- C21.0Malignant neoplasm of anus, unspecified
- C21.1Malignant neoplasm of anal canal
- C21.2Malignant neoplasm of cloacogenic zone
- C21.8Malignant neoplasm of overlapping sites of rectum, anus and anal canal
- C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
- D12.6Benign neoplasm of colon, unspecified
- K63.5Polyp of colon
- Z12.11Encounter for screening for malignant neoplasm of colon
- Z15.060Genetic susceptibility to colorectal cancer
- Z85.038Personal history of other malignant neoplasm of large intestine
- Z85.048Personal history of other malignant neoplasm of rectum, rectosigmoid junction, and anus
- Z86.0100Personal history of colon polyps, unspecified
- Z86.0101Personal history of adenomatous and serrated colon polyps
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