Is ICD-10-CM code E88 billable?

No, E88 (Other and unspecified metabolic disorders) is a non-billable ICD-10-CM code. It must be coded to a more specific subcategory before it can be used for reimbursement.

What chapter does ICD-10-CM code E88 belong to?

E88 belongs to Chapter 4 of the ICD-10-CM tabular list: E00–E89 (Endocrine, Nutritional and Metabolic Diseases).

E88Not billable, use a more specific code below

Other and unspecified metabolic disorders

In Metabolic disorders (E70-E88), chapter 4: Endocrine, Nutritional and Metabolic Diseases

24 billable codes under E88: 1 is an MCC, 6 are a CC; 2 map to HCC 50 (Amyloidosis, Porphyria, and Other Specified Metabolic Disorders).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

Instructional notes

Excludes1: not coded here, use a different code

histiocytosis X (chronic) (C96.6)

Use additional code: add a second code for this, listed after this one

codes for associated conditions

Also applies, from Metabolic disorders (E70-E88)

These notes sit on E70-E88 and apply to every code under it, including E88.

Excludes1: not coded here, use a different code

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2: not included here, code separately if applicable

Ehlers-Danlos syndromes (Q79.6-)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Covers diabetes mellitus coding, including type, insulin and drug use, pump malfunction and secondary diabetes, plus obesity and obesity class codes.

Diabetes mellitus (page 39)
Obesity (page 42)

Read Section I.C.4 (page 39)

All codes under E88

E88 can't be used on a claim. Pick a billable code below; grey headings group them.

E88 MS-DRGs

As the principal diagnosis, the billable codes under E88 group to these 17 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

DRG 642 Inborn and Other Disorders of Metabolism (21 of 24 codes)
DRG 826 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC (2 of 24 codes)
DRG 827 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC (2 of 24 codes)
DRG 828 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures without CC/MCC (2 of 24 codes)
DRG 829 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures with CC/MCC (2 of 24 codes)
DRG 830 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures without CC/MCC (2 of 24 codes)
DRG 843 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with MCC (2 of 24 codes)
DRG 844 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with CC (2 of 24 codes)
DRG 845 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses without CC/MCC (2 of 24 codes)
DRG 673 Other Kidney and Urinary Tract Procedures with MCC (1 of 24 codes)
DRG 674 Other Kidney and Urinary Tract Procedures with CC (1 of 24 codes)
DRG 675 Other Kidney and Urinary Tract Procedures without CC/MCC (1 of 24 codes)
DRG 682 Renal Failure with MCC (1 of 24 codes)
DRG 683 Renal Failure with CC (1 of 24 codes)
DRG 684 Renal Failure without CC/MCC (1 of 24 codes)
DRG 791 Prematurity with Major Problems (1 of 24 codes)
DRG 793 Full Term Neonate with Major Problems (1 of 24 codes)

Other codes that refer to E88

Notes on these codes point to E88.

CH10 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH11 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH12 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH13 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH14 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH16 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH17 Excludes2: inborn errors of metabolism (E70-E88)
CH3 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH6 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH7 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH8 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
CH9 Excludes2: endocrine, nutritional and metabolic diseases (E00-E88)
G11 Excludes2: metabolic disorders (E70-E88)
G63 Code First: metabolic diseases (E70-E88)
G71 Excludes2: metabolic disorders (E70-E88)
H42 Code First: specified metabolic disorder (E70-E88)
N25.0 Excludes2: metabolic disorders classifiable to E70-E88
N25.81 Excludes2: metabolic disorders classifiable to E70-E88
P59 Excludes1: jaundice due to inborn errors of metabolism (E70-E88)
Z83.4 Includes: Conditions classifiable to E00-E07, E15-E88

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.