All ICD10 Codes

E88.8

Non-Billable
ChapterE00–E89
Ranksubcategory
Official Description

Other specified metabolic disorders

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89).
General instructions are available for the parent sections:
View CH4 NotesView E70-E88 NotesView E88 Notes

Clinical Hierarchy

CH4Endocrine, nutritional and metabolic diseases (E00-E89)
E70-E88Metabolic disorders (E70-E88)
E88Other and unspecified metabolic disorders
E88.8Other specified metabolic disorders
E88.81Metabolic syndrome and other insulin resistance
E88.82Obesity due to disruption of MC4R pathway
E88.89Other specified metabolic disorders

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to E88.8:

categoryE88
Other and unspecified metabolic disorders
View context instructions
blockE70-E88
Metabolic disorders (E70-E88)
View context instructions
chapterCH4
Endocrine, nutritional and metabolic diseases (E00-E89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to E88.8. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Adenolipomatosis, Launois-Bensaude1 unique routes
Direct index entry→E88.8
Deficiency, deficient1 unique routes
dihydropyrimidine dehydrogenase (DPD)→E88.8
Dihydropyrimidine dehydrogenase disease (DPD)1 unique routes
Direct index entry→E88.8
Disease, diseased1 unique routes
Erdheim-Chester (ECD)→E88.8
Disorder (of)1 unique routes
metabolism NOS
specified NEC→E88.8
DPD (dihydropyrimidine dehydrogenase deficiency)1 unique routes
Direct index entry→E88.8
Dysmetabolic syndrome X1 unique routes
Direct index entry→E88.8
Hoffa-Kastert disease1 unique routes
Direct index entry→E88.8
Hoffa's disease1 unique routes
Direct index entry→E88.8
Ketosis NEC1 unique routes
Direct index entry→E88.8
Launois-Bensaude adenolipomatosis1 unique routes
Direct index entry→E88.8
Lipomatosis1 unique routes
Launois-Bensaude→E88.8
Liposynovitis prepatellaris1 unique routes
Direct index entry→E88.8
Madelung's1 unique routes
disease
symmetrical lipomas, neck→E88.8
Metabolic syndrome1 unique routes
Direct index entry→E88.8
Obesity8 unique routes
due to(8 variants)
disruption of MC4R pathway→E88.8
gene mutation(7 variants)
leptin (LEP)→E88.8
leptin receptor (LEPR)→E88.8
melanocortin 4 Receptor (MC4R)→E88.8
nuclear receptor coactivator 1 (NCOA1)→E88.8
proopiomelanocortin (POMC)→E88.8
proprotein convertase subtilisin/kexin type 1 (PCSK1)→E88.8
src homology 2B adaptor signaling protein (SH2B1)→E88.8
Resistance, resistant (to)2 unique routes
insulin→E88.8(2 variants)
specified type NEC→E88.8

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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