E88.41

Billable

ChapterE00–E89

Ranksubcategory

Official Description

MELAS syndrome

Metadata & Insights

•2026 ICD-10-CM Edition - Effective October 1, 2025.
•Billable/specific code (valid for reimbursement).
•Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89).

Instructional Notes

Includes

Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes

General instructions are available for the parent sections:

View CH4 Notes View E70-E88 Notes View E88 Notes View E88.4 Notes

Clinical Hierarchy

CH4Endocrine, nutritional and metabolic diseases (E00-E89)

E70-E88Metabolic disorders (E70-E88)

E88Other and unspecified metabolic disorders

E88.4Mitochondrial metabolism disorders

E88.41MELAS syndrome

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to E88.41:

subcategoryE88.4

Mitochondrial metabolism disorders

View context instructions

categoryE88

Other and unspecified metabolic disorders

View context instructions

blockE70-E88

Metabolic disorders (E70-E88)

View context instructions

chapterCH4

Endocrine, nutritional and metabolic diseases (E00-E89)

View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to E88.41. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

3 raw paths

Disorder (of)1 unique routes

metabolism NOS

mitochondrial

MELAS syndrome→E88.41

MELAS syndrome1 unique routes

Direct index entry→E88.41

Syndrome1 unique routes

MELAS→E88.41

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 642

Inborn and Other Disorders of Metabolism

Cross Reference

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