Complications following infusion, transfusion and therapeutic injection
In Complications of surgical and medical care, not elsewhere classified (T80-T88), chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes
114 billable codes under T80: 1 is an MCC, 33 are a CC; none map to an HCC.A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment.
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Instructional notes
Includes: conditions that are coded here
- complications following perfusion
Excludes2: not included here, code separately if applicable
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
Also applies, from Complications of surgical and medical care, not elsewhere classified (T80-T88)
These notes sit on T80-T88 and apply to every code under it, including T80.
Excludes2: not included here, code separately if applicable
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Use additional code: add a second code for this, listed after this one
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
- Section I.C.19.g Complications of care (page 85), covers T80
Use T86 plus a code for the complication only when it affects transplanted organ function. Body system complication codes are sequenced first unless indexed to a T code, and device pain also gets G89.18 or G89.28.
Other Chapter 19 topics:
- Application of 7th Characters in Chapter 19 (page 77)
- Coding of Injuries (page 78)
- Coding of Traumatic Fractures (page 79)
- Coding of Burns and Corrosions (page 80)
- Adverse Effects, Poisoning, Underdosing and Toxic Effects (page 82)
- Adult and child abuse, neglect and other maltreatment (page 85)
All codes under T80
T80 can't be used on a claim. Pick a billable code below; grey headings group them.
- T80.0Air embolism following infusion, transfusion and therapeutic injection
- T80.0XXAAir embolism following infusion, transfusion and therapeutic injection, initial encounter
- T80.0XXDAir embolism following infusion, transfusion and therapeutic injection, subsequent encounter
- T80.0XXSAir embolism following infusion, transfusion and therapeutic injection, sequela
- T80.1Vascular complications following infusion, transfusion and therapeutic injection
- T80.1XXAVascular complications following infusion, transfusion and therapeutic injection, initial encounter
- T80.1XXDVascular complications following infusion, transfusion and therapeutic injection, subsequent encounter
- T80.1XXSVascular complications following infusion, transfusion and therapeutic injection, sequela
- T80.2Infections following infusion, transfusion and therapeutic injection
- T80.21Infection due to central venous catheter
- T80.211Bloodstream infection due to central venous catheter
- T80.211ABloodstream infection due to central venous catheter, initial encounter
- T80.211DBloodstream infection due to central venous catheter, subsequent encounter
- T80.211SBloodstream infection due to central venous catheter, sequela
- T80.212Local infection due to central venous catheter
- T80.212ALocal infection due to central venous catheter, initial encounter
- T80.212DLocal infection due to central venous catheter, subsequent encounter
- T80.212SLocal infection due to central venous catheter, sequela
- T80.218Other infection due to central venous catheter
- T80.218AOther infection due to central venous catheter, initial encounter
- T80.218DOther infection due to central venous catheter, subsequent encounter
- T80.218SOther infection due to central venous catheter, sequela
- T80.219Unspecified infection due to central venous catheter
- T80.219AUnspecified infection due to central venous catheter, initial encounter
- T80.219DUnspecified infection due to central venous catheter, subsequent encounter
- T80.219SUnspecified infection due to central venous catheter, sequela
- T80.22Acute infection following transfusion, infusion, or injection of blood and blood products
- T80.22XAAcute infection following transfusion, infusion, or injection of blood and blood products, initial encounter
- T80.22XDAcute infection following transfusion, infusion, or injection of blood and blood products, subsequent encounter
- T80.22XSAcute infection following transfusion, infusion, or injection of blood and blood products, sequela
- T80.29Infection following other infusion, transfusion and therapeutic injection
- T80.29XAInfection following other infusion, transfusion and therapeutic injection, initial encounter
- T80.29XDInfection following other infusion, transfusion and therapeutic injection, subsequent encounter
- T80.29XSInfection following other infusion, transfusion and therapeutic injection, sequela
- T80.3ABO incompatibility reaction due to transfusion of blood or blood products
- T80.30ABO incompatibility reaction due to transfusion of blood or blood products, unspecified
- T80.30XAABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.30XDABO incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
- T80.30XSABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
- T80.31ABO incompatibility with hemolytic transfusion reaction
- T80.310ABO incompatibility with acute hemolytic transfusion reaction
- T80.310AABO incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.310DABO incompatibility with acute hemolytic transfusion reaction, subsequent encounter
- T80.310SABO incompatibility with acute hemolytic transfusion reaction, sequela
- T80.311ABO incompatibility with delayed hemolytic transfusion reaction
- T80.311AABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.311DABO incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
- T80.311SABO incompatibility with delayed hemolytic transfusion reaction, sequela
- T80.319ABO incompatibility with hemolytic transfusion reaction, unspecified
- T80.319AABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.319DABO incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
- T80.319SABO incompatibility with hemolytic transfusion reaction, unspecified, sequela
- T80.39Other ABO incompatibility reaction due to transfusion of blood or blood products
- T80.39XAOther ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
- T80.39XDOther ABO incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
- T80.39XSOther ABO incompatibility reaction due to transfusion of blood or blood products, sequela
- T80.4Rh incompatibility reaction due to transfusion of blood or blood products
- T80.40Rh incompatibility reaction due to transfusion of blood or blood products, unspecified
- T80.40XARh incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.40XDRh incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
- T80.40XSRh incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
- T80.41Rh incompatibility with hemolytic transfusion reaction
- T80.410Rh incompatibility with acute hemolytic transfusion reaction
- T80.410ARh incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.410DRh incompatibility with acute hemolytic transfusion reaction, subsequent encounter
- T80.410SRh incompatibility with acute hemolytic transfusion reaction, sequela
- T80.411Rh incompatibility with delayed hemolytic transfusion reaction
- T80.411ARh incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.411DRh incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
- T80.411SRh incompatibility with delayed hemolytic transfusion reaction, sequela
- T80.419Rh incompatibility with hemolytic transfusion reaction, unspecified
- T80.419ARh incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.419DRh incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
- T80.419SRh incompatibility with hemolytic transfusion reaction, unspecified, sequela
- T80.49Other Rh incompatibility reaction due to transfusion of blood or blood products
- T80.49XAOther Rh incompatibility reaction due to transfusion of blood or blood products, initial encounter
- T80.49XDOther Rh incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
- T80.49XSOther Rh incompatibility reaction due to transfusion of blood or blood products, sequela
- T80.5Anaphylactic reaction due to serum
- T80.51Anaphylactic reaction due to administration of blood and blood products
- T80.51XAAnaphylactic reaction due to administration of blood and blood products, initial encounter
- T80.51XDAnaphylactic reaction due to administration of blood and blood products, subsequent encounter
- T80.51XSAnaphylactic reaction due to administration of blood and blood products, sequela
- T80.52Anaphylactic reaction due to vaccination
- T80.52XAAnaphylactic reaction due to vaccination, initial encounter
- T80.52XDAnaphylactic reaction due to vaccination, subsequent encounter
- T80.52XSAnaphylactic reaction due to vaccination, sequela
- T80.59Anaphylactic reaction due to other serum
- T80.59XAAnaphylactic reaction due to other serum, initial encounter
- T80.59XDAnaphylactic reaction due to other serum, subsequent encounter
- T80.59XSAnaphylactic reaction due to other serum, sequela
- T80.6Other serum reactions
- T80.61Other serum reaction due to administration of blood and blood products
- T80.61XAOther serum reaction due to administration of blood and blood products, initial encounter
- T80.61XDOther serum reaction due to administration of blood and blood products, subsequent encounter
- T80.61XSOther serum reaction due to administration of blood and blood products, sequela
- T80.62Other serum reaction due to vaccination
- T80.62XAOther serum reaction due to vaccination, initial encounter
- T80.62XDOther serum reaction due to vaccination, subsequent encounter
- T80.62XSOther serum reaction due to vaccination, sequela
- T80.69Other serum reaction due to other serum
- T80.69XAOther serum reaction due to other serum, initial encounter
- T80.69XDOther serum reaction due to other serum, subsequent encounter
- T80.69XSOther serum reaction due to other serum, sequela
- T80.8Other complications following infusion, transfusion and therapeutic injection
- T80.81Extravasation of vesicant agent
- T80.810Extravasation of vesicant antineoplastic chemotherapy
- T80.810AExtravasation of vesicant antineoplastic chemotherapy, initial encounter
- T80.810DExtravasation of vesicant antineoplastic chemotherapy, subsequent encounter
- T80.810SExtravasation of vesicant antineoplastic chemotherapy, sequela
- T80.818Extravasation of other vesicant agent
- T80.818AExtravasation of other vesicant agent, initial encounter
- T80.818DExtravasation of other vesicant agent, subsequent encounter
- T80.818SExtravasation of other vesicant agent, sequela
- T80.82Complication of immune effector cellular therapy
- T80.82XAComplication of immune effector cellular therapy, initial encounter
- T80.82XDComplication of immune effector cellular therapy, subsequent encounter
- T80.82XSComplication of immune effector cellular therapy, sequela
- T80.89Other complications following infusion, transfusion and therapeutic injection
- T80.89XAOther complications following infusion, transfusion and therapeutic injection, initial encounter
- T80.89XDOther complications following infusion, transfusion and therapeutic injection, subsequent encounter
- T80.89XSOther complications following infusion, transfusion and therapeutic injection, sequela
- T80.9Unspecified complication following infusion, transfusion and therapeutic injection
- T80.90Unspecified complication following infusion and therapeutic injection
- T80.90XAUnspecified complication following infusion and therapeutic injection, initial encounter
- T80.90XDUnspecified complication following infusion and therapeutic injection, subsequent encounter
- T80.90XSUnspecified complication following infusion and therapeutic injection, sequela
- T80.91Hemolytic transfusion reaction, unspecified incompatibility
- T80.910Acute hemolytic transfusion reaction, unspecified incompatibility
- T80.910AAcute hemolytic transfusion reaction, unspecified incompatibility, initial encounter
- T80.910DAcute hemolytic transfusion reaction, unspecified incompatibility, subsequent encounter
- T80.910SAcute hemolytic transfusion reaction, unspecified incompatibility, sequela
- T80.911Delayed hemolytic transfusion reaction, unspecified incompatibility
- T80.911ADelayed hemolytic transfusion reaction, unspecified incompatibility, initial encounter
- T80.911DDelayed hemolytic transfusion reaction, unspecified incompatibility, subsequent encounter
- T80.911SDelayed hemolytic transfusion reaction, unspecified incompatibility, sequela
- T80.919Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed
- T80.919AHemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, initial encounter
- T80.919DHemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, subsequent encounter
- T80.919SHemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed, sequela
- T80.92Unspecified transfusion reaction
- T80.92XAUnspecified transfusion reaction, initial encounter
- T80.92XDUnspecified transfusion reaction, subsequent encounter
- T80.92XSUnspecified transfusion reaction, sequela
- T80.ANon-ABO incompatibility reaction due to transfusion of blood or blood products
- T80.A0Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified
- T80.A0XANon-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
- T80.A0XDNon-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
- T80.A0XSNon-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
- T80.A1Non-ABO incompatibility with hemolytic transfusion reaction
- T80.A10Non-ABO incompatibility with acute hemolytic transfusion reaction
- T80.A10ANon-ABO incompatibility with acute hemolytic transfusion reaction, initial encounter
- T80.A10DNon-ABO incompatibility with acute hemolytic transfusion reaction, subsequent encounter
- T80.A10SNon-ABO incompatibility with acute hemolytic transfusion reaction, sequela
- T80.A11Non-ABO incompatibility with delayed hemolytic transfusion reaction
- T80.A11ANon-ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
- T80.A11DNon-ABO incompatibility with delayed hemolytic transfusion reaction, subsequent encounter
- T80.A11SNon-ABO incompatibility with delayed hemolytic transfusion reaction, sequela
- T80.A19Non-ABO incompatibility with hemolytic transfusion reaction, unspecified
- T80.A19ANon-ABO incompatibility with hemolytic transfusion reaction, unspecified, initial encounter
- T80.A19DNon-ABO incompatibility with hemolytic transfusion reaction, unspecified, subsequent encounter
- T80.A19SNon-ABO incompatibility with hemolytic transfusion reaction, unspecified, sequela
- T80.A9Other non-ABO incompatibility reaction due to transfusion of blood or blood products
- T80.A9XAOther non-ABO incompatibility reaction due to transfusion of blood or blood products, initial encounter
- T80.A9XDOther non-ABO incompatibility reaction due to transfusion of blood or blood products, subsequent encounter
- T80.A9XSOther non-ABO incompatibility reaction due to transfusion of blood or blood products, sequela
T80 MS-DRGs
As the principal diagnosis, the billable codes under T80 group to these 24 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 922 Other Injury, Poisoning and Toxic Effect Diagnoses with MCC (38 of 114 codes)
- DRG 923 Other Injury, Poisoning and Toxic Effect Diagnoses without MCC (38 of 114 codes)
- DRG 949 Aftercare with CC/MCC (38 of 114 codes)
- DRG 950 Aftercare without CC/MCC (38 of 114 codes)
- DRG 791 Prematurity with Major Problems (34 of 114 codes)
- DRG 793 Full Term Neonate with Major Problems (34 of 114 codes)
- DRG 811 Red Blood Cell Disorders with MCC (20 of 114 codes)
- DRG 812 Red Blood Cell Disorders without MCC (20 of 114 codes)
- DRG 314 Other Circulatory System Diagnoses with MCC (8 of 114 codes)
- DRG 315 Other Circulatory System Diagnoses with CC (8 of 114 codes)
- DRG 316 Other Circulatory System Diagnoses without CC/MCC (8 of 114 codes)
- DRG 915 Allergic Reactions with MCC (6 of 114 codes)
- DRG 916 Allergic Reactions without MCC (6 of 114 codes)
- DRG 856 Postoperative or Post-Traumatic Infections with O.R. Procedures with MCC (2 of 114 codes)
- DRG 857 Postoperative or Post-Traumatic Infections with O.R. Procedures with CC (2 of 114 codes)
- DRG 858 Postoperative or Post-Traumatic Infections with O.R. Procedures without CC/MCC (2 of 114 codes)
- DRG 867 Other Infectious and Parasitic Diseases Diagnoses with MCC (2 of 114 codes)
- DRG 868 Other Infectious and Parasitic Diseases Diagnoses with CC (2 of 114 codes)
- DRG 869 Other Infectious and Parasitic Diseases Diagnoses without CC/MCC (2 of 114 codes)
- DRG 175 Pulmonary Embolism with MCC or Acute Cor Pulmonale (1 of 114 codes)
- DRG 176 Pulmonary Embolism without MCC (1 of 114 codes)
- DRG 814 Reticuloendothelial and Immunity Disorders with MCC (1 of 114 codes)
- DRG 815 Reticuloendothelial and Immunity Disorders with CC (1 of 114 codes)
- DRG 816 Reticuloendothelial and Immunity Disorders without CC/MCC (1 of 114 codes)
Other codes that refer to T80
Notes on these codes point to T80.
- P00.89 Includes: Newborn affected by conditions classifiable to T80-T88
- T45.8 Excludes2: transfusion reactions (T80.-)
- T78 Excludes2: complications of surgical and medical care NEC (T80-T88)
- T79 Excludes2: complications occurring during or following medical procedures (T80-T88)
- T79 Excludes2: complications of surgical and medical care NEC (T80-T88)
- T81 Excludes2: complications following infusion, transfusion and therapeutic injection (T80.-)
- T88 Excludes2: complication following infusion, transfusion and therapeutic injection (T80.-)
- T88.7 Excludes1: specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)
Code history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
