Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)
chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes
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Instructional notes
Includes: conditions that are coded here
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Excludes1: not coded here, use a different code
- toxic reaction to local anesthesia in pregnancy (O29.3-)
Excludes2: not included here, code separately if applicable
Code first: code the underlying condition first, then this code
Use additional code: add a second code for this, listed after this one
- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
- Section I.C.19.e Adverse Effects, Poisoning, Underdosing and Toxic Effects (page 82), covers T36-T50
For adverse effects, code the effect first, then T36-T50 with character 5. Sequence poisonings (unknown intent coded accidental) and toxic effects (T51-T65) first; underdosing (character 6) is never first-listed.
Other Chapter 19 topics:
- Application of 7th Characters in Chapter 19 (page 77)
- Coding of Injuries (page 78)
- Coding of Traumatic Fractures (page 79)
- Coding of Burns and Corrosions (page 80)
- Adult and child abuse, neglect and other maltreatment (page 85)
- Complications of care (page 85)
Codes under T36-T50
T36-T50 can't be used on a claim. Pick a billable code below; grey headings group them.
- T36Poisoning by, adverse effect of and underdosing of systemic antibiotics
- T37Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics
- T38Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified
- T39Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics
- T40Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens]
- T41Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases
- T42Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
- T43Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
- T44Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system
- T45Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
- T46Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system
- T47Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system
- T48Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
- T49Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
- T50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
T36-T50 MS-DRGs
This code does not group to an MS-DRG as a principal diagnosis.
Other codes that refer to T36-T50
Notes on these codes point to T36-T50.
- D46 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D52.1 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D59.0 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D59.2 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D59.39 Use Additional Code: code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)
- D61.1 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D64.2 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D70.2 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D72.12 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- D84.821 Use Additional Code: code for adverse effect if applicable, to identify adverse effect of drug (T36-T50 with fifth or six character 5)
- D89.3 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E03.2 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E06.4 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E09 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E16.0 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E22.1 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E23.1 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E24.2 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E25.8 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- E27.3 Use Additional Code: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Antibiotics
Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.
Read more about antibiotics on MedlinePlusDrug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
Read more about drug reactions on MedlinePlus