Is ICD-10-CM code E72 billable?

No, E72 (Other disorders of amino-acid metabolism) is a non-billable ICD-10-CM code. It must be coded to a more specific subcategory before it can be used for reimbursement.

What chapter does ICD-10-CM code E72 belong to?

E72 belongs to Chapter 4 of the ICD-10-CM tabular list: E00–E89 (Endocrine, Nutritional and Metabolic Diseases).

E72Not billable, use a more specific code below

Other disorders of amino-acid metabolism

In Metabolic disorders (E70-E88), chapter 4: Endocrine, Nutritional and Metabolic Diseases

31 billable codes under E72: 27 are a CC; 3 map to HCC 50 (Amyloidosis, Porphyria, and Other Specified Metabolic Disorders).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

Instructional notes

Excludes1: not coded here, use a different code

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

Also applies, from Metabolic disorders (E70-E88)

These notes sit on E70-E88 and apply to every code under it, including E72.

Excludes1: not coded here, use a different code

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2: not included here, code separately if applicable

Ehlers-Danlos syndromes (Q79.6-)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Covers diabetes mellitus coding, including type, insulin and drug use, pump malfunction and secondary diabetes, plus obesity and obesity class codes.

Diabetes mellitus (page 39)
Obesity (page 42)

Read Section I.C.4 (page 39)

All codes under E72

E72 can't be used on a claim. Pick a billable code below; grey headings group them.

E72 MS-DRGs

As the principal diagnosis, the billable codes under E72 group to MS-DRG 642, 695, or 696 (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

DRG 642 Inborn and Other Disorders of Metabolism (27 of 31 codes)
DRG 695 Kidney and Urinary Tract Signs and Symptoms with MCC (4 of 31 codes)
DRG 696 Kidney and Urinary Tract Signs and Symptoms without MCC (4 of 31 codes)

Other codes that refer to E72

Notes on these codes point to E72.

R79 Excludes1: specific findings indicating disorder of amino-acid metabolism (E70-E72)
R79.83 Excludes1: disorders of amino-acid metabolism (E70-E72)
R80-R82 Excludes1: specific findings indicating disorder of amino-acid metabolism (E70-E72)

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Amino Acid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Your digestive system breaks the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body. If you have a metabolic disorder, something goes wrong with this process.

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.