Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • D60.8|

    Other acquired pure red cell aplasias

  • D60.9|

    Acquired pure red cell aplasia, unspecified

  • D61.01|

    Constitutional (pure) red blood cell aplasia

  • D61.02|

    Shwachman-Diamond syndrome

  • D61.03|

    Fanconi anemia

  • D61.09|

    Other constitutional aplastic anemia

  • D61.1|

    Drug-induced aplastic anemia

  • D61.2|

    Aplastic anemia due to other external agents

  • D61.3|

    Idiopathic aplastic anemia

  • D61.810|

    Antineoplastic chemotherapy induced pancytopenia

  • D61.811|

    Other drug-induced pancytopenia

  • D61.818|

    Other pancytopenia

  • D61.82|

    Myelophthisis

  • D61.89|

    Other specified aplastic anemias and other bone marrow failure syndromes

  • D61.9|

    Aplastic anemia, unspecified

  • D62|

    Acute posthemorrhagic anemia

  • D63.0|

    Anemia in neoplastic disease

  • D63.1|

    Anemia in chronic kidney disease

  • D63.8|

    Anemia in other chronic diseases classified elsewhere

  • D64.0|

    Hereditary sideroblastic anemia

  • D64.1|

    Secondary sideroblastic anemia due to disease

  • D64.2|

    Secondary sideroblastic anemia due to drugs and toxins

  • D64.3|

    Other sideroblastic anemias

  • D64.4|

    Congenital dyserythropoietic anemia

  • D64.81|

    Anemia due to antineoplastic chemotherapy

  • D64.89|

    Other specified anemias

  • D64.9|

    Anemia, unspecified

  • D65|

    Disseminated intravascular coagulation [defibrination syndrome]

  • D66|

    Hereditary factor VIII deficiency

  • D67|

    Hereditary factor IX deficiency

  • D68.00|

    Von Willebrand disease, unspecified

  • D68.01|

    Von Willebrand disease, type 1

  • D68.020|

    Von Willebrand disease, type 2A

  • D68.021|

    Von Willebrand disease, type 2B

  • D68.022|

    Von Willebrand disease, type 2M

  • D68.023|

    Von Willebrand disease, type 2N

  • D68.029|

    Von Willebrand disease, type 2, unspecified

  • D68.03|

    Von Willebrand disease, type 3

  • D68.04|

    Acquired von Willebrand disease

  • D68.09|

    Other von Willebrand disease

  • D68.1|

    Hereditary factor XI deficiency

  • D68.2|

    Hereditary deficiency of other clotting factors

  • D68.311|

    Acquired hemophilia

  • D68.312|

    Antiphospholipid antibody with hemorrhagic disorder

  • D68.318|

    Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

  • D68.32|

    Hemorrhagic disorder due to extrinsic circulating anticoagulants

  • D68.4|

    Acquired coagulation factor deficiency

  • D68.51|

    Activated protein C resistance

  • D68.52|

    Prothrombin gene mutation

  • D68.59|

    Other primary thrombophilia

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