Is ICD-10-CM code E85 billable?

No, E85 (Amyloidosis) is a non-billable ICD-10-CM code. It must be coded to a more specific subcategory before it can be used for reimbursement.

What chapter does ICD-10-CM code E85 belong to?

E85 belongs to Chapter 4 of the ICD-10-CM tabular list: E00–E89 (Endocrine, Nutritional and Metabolic Diseases).

E85Not billable, use a more specific code below

Amyloidosis

In Metabolic disorders (E70-E88), chapter 4: Endocrine, Nutritional and Metabolic Diseases

9 billable codes under E85: all are a CC; all map to HCC 50 (Amyloidosis, Porphyria, and Other Specified Metabolic Disorders).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

Instructional notes

Excludes2: not included here, code separately if applicable

Alzheimer's disease (G30.0-)

Also applies, from Metabolic disorders (E70-E88)

These notes sit on E70-E88 and apply to every code under it, including E85.

Excludes1: not coded here, use a different code

androgen insensitivity syndrome (E34.5-)
congenital adrenal hyperplasia (E25.0)
hemolytic anemias attributable to enzyme disorders (D55.-)
Marfan syndrome (Q87.4-)
5-alpha-reductase deficiency (E29.1)

Excludes2: not included here, code separately if applicable

Ehlers-Danlos syndromes (Q79.6-)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Covers diabetes mellitus coding, including type, insulin and drug use, pump malfunction and secondary diabetes, plus obesity and obesity class codes.

Diabetes mellitus (page 39)
Obesity (page 42)

Read Section I.C.4 (page 39)

All codes under E85

E85 can't be used on a claim. Pick a billable code below; grey headings group them.

E85 MS-DRGs

As the principal diagnosis, all 9 billable codes under E85 group to MS-DRG 545, 546, or 547 (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

Other codes that refer to E85

Notes on these codes point to E85.

D77 Code First: amyloidosis (E85.-)
E27.1 Excludes1: amyloidosis (E85.-)
G32.8 Code First: amyloidosis cerebral degeneration (E85.-)
G63 Code First: amyloidosis (E85.-)
G99.0 Code First: amyloidosis (E85.-)
G99.8 Code First: amyloidosis (E85.-)
H42 Code First: amyloidosis (E85.-)
I43 Code First: amyloidosis (E85.-)
I68.0 Code First: underlying amyloidosis (E85.-)
I79.8 Code First: amyloidosis (E85.-)
J99 Code First: amyloidosis (E85.-)
K76 Excludes2: amyloid degeneration of liver (E85.-)
K77 Code First: amyloidosis (E85.-)
L99 Code First: amyloidosis (E85.-)
M14.8 Code First: amyloidosis (E85.-)
M60-M63 Excludes1: myopathy in amyloidosis (E85.-)
N07 Excludes2: hereditary amyloid nephropathy (E85.-)
N07 Excludes2: non-neuropathic heredofamilial amyloidosis (E85.-)
N08 Code First: amyloidosis (E85.-)
N29 Code First: amyloidosis (E85.-)

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Amyloidosis

Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.