All ICD10 Codes
E35Billable, valid for claims from October 1, 2026

Disorders of endocrine glands in diseases classified elsewhere

In Disorders of other endocrine glands (E20-E35), chapter 4: Endocrine, Nutritional and Metabolic Diseases

  • E35 is billable and valid on claims for FY 2027. If the record has more detail, check the other codes under E20-E35 below.
  • As a secondary diagnosis it is not a CC or MCC, so it doesn't raise the MS-DRG payment.
  • Doesn't count toward a Medicare Advantage risk score (no HCC in V28).
  • AHRQ's Chronic Condition Indicator classes it as not chronic (an acute or short-term condition).
  • Can't be the principal diagnosis: code the underlying condition first. (Manifestation list)

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Instructional notes

Excludes1: not coded here, use a different code

  • Echinococcus granulosus infection of thyroid gland (B67.3)
  • meningococcal hemorrhagic adrenalitis (A39.1)
  • syphilis of endocrine gland (A52.79)
  • tuberculosis of adrenal gland, except calcification (A18.7)
  • tuberculosis of endocrine gland NEC (A18.82)
  • tuberculosis of thyroid gland (A18.81)
  • Waterhouse-Friderichsen syndrome (A39.1)

Code first: code the underlying condition first, then this code

  • underlying disease, such as:
  • late congenital syphilis of thymus gland [Dubois disease] (A50.59)

Also applies, from Disorders of other endocrine glands (E20-E35)

These notes sit on E20-E35 and apply to every code under it, including E35.

Excludes1: not coded here, use a different code

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Covers diabetes mellitus coding, including type, insulin and drug use, pump malfunction and secondary diabetes, plus obesity and obesity class codes.

Read Section I.C.4 (page 39)

Other codes under E20-E35

Disorders of other endocrine glands (E20-E35)

E35 MS-DRGs

This code does not group to an MS-DRG as a principal diagnosis.

Related conditions

Grouped by AHRQ's Clinical Classifications Software Refined (CCSR), which sorts every diagnosis code into clinically meaningful categories.

E35 is in Other specified and unspecified endocrine disorders (END015), with 101 codes. Others in it:

  • A18.7 Tuberculosis of adrenal glands
  • A18.82 Tuberculosis of other endocrine glands
  • A39.1 Waterhouse-Friderichsen syndrome
  • E15 Nondiabetic hypoglycemic coma
  • E16.0 Drug-induced hypoglycemia without coma
  • E16.1 Other hypoglycemia
  • E16.2 Hypoglycemia, unspecified
  • E16.3 Increased secretion of glucagon

Medicare coverage articles listing E35

These 8 Medicare billing and coding articles list E35 as a diagnosis that supports medical necessity for the services they cover. From the CMS Medicare Coverage Database; check your own contractor's article before billing.

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read more about endocrine diseases on MedlinePlus

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.

ICD-9-CM equivalent

Legacy crosswalk from the CMS General Equivalence Mappings (last updated 2018).

  • 246.8 Other specified disorders of thyroid (approximate)
  • 255.8 Other specified disorders of adrenal glands (approximate)
  • 259.8 Other specified endocrine disorders (approximate)
ICD-9 to ICD-10 converter