Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • D73.3

    Abscess of spleen

  • D73.4

    Cyst of spleen

  • D73.5

    Infarction of spleen

  • D73.8

    Other diseases of spleen

  • D73.81

    Neutropenic splenomegaly

  • D73.89

    Other diseases of spleen

  • D73.9

    Disease of spleen, unspecified

  • D74

    Methemoglobinemia

  • D74.0

    Congenital methemoglobinemia

  • D74.8

    Other methemoglobinemias

  • D74.9

    Methemoglobinemia, unspecified

  • D75

    Other and unspecified diseases of blood and blood-forming organs

  • D75.0

    Familial erythrocytosis

  • D75.1

    Secondary polycythemia

  • D75.8

    Other specified diseases of blood and blood-forming organs

  • D75.81

    Myelofibrosis

  • D75.82

    Heparin induced thrombocytopenia (HIT)

  • D75.821

    Non-immune heparin-induced thrombocytopenia

  • D75.822

    Immune-mediated heparin-induced thrombocytopenia

  • D75.828

    Other heparin-induced thrombocytopenia syndrome

  • D75.829

    Heparin-induced thrombocytopenia, unspecified

  • D75.83

    Thrombocytosis

  • D75.838

    Other thrombocytosis

  • D75.839

    Thrombocytosis, unspecified

  • D75.84

    Other platelet-activating anti-PF4 disorders

  • D75.89

    Other specified diseases of blood and blood-forming organs

  • D75.9

    Disease of blood and blood-forming organs, unspecified

  • D75.A

    Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

  • D76

    Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

  • D76.1

    Hemophagocytic lymphohistiocytosis

  • D76.2

    Hemophagocytic syndrome, infection-associated

  • D76.3

    Other histiocytosis syndromes

  • D77

    Other disorders of blood and blood-forming organs in diseases classified elsewhere

  • D78

    Intraoperative and postprocedural complications of the spleen

  • D78.0

    Intraoperative hemorrhage and hematoma of the spleen complicating a procedure

  • D78.01

    Intraoperative hemorrhage and hematoma of the spleen complicating a procedure on the spleen

  • D78.02

    Intraoperative hemorrhage and hematoma of the spleen complicating other procedure

  • D78.1

    Accidental puncture and laceration of the spleen during a procedure

  • D78.11

    Accidental puncture and laceration of the spleen during a procedure on the spleen

  • D78.12

    Accidental puncture and laceration of the spleen during other procedure

  • D78.2

    Postprocedural hemorrhage of the spleen following a procedure

  • D78.21

    Postprocedural hemorrhage of the spleen following a procedure on the spleen

  • D78.22

    Postprocedural hemorrhage of the spleen following other procedure

  • D78.3

    Postprocedural hematoma and seroma of the spleen following a procedure

  • D78.31

    Postprocedural hematoma of the spleen following a procedure on the spleen

  • D78.32

    Postprocedural hematoma of the spleen following other procedure

  • D78.33

    Postprocedural seroma of the spleen following a procedure on the spleen

  • D78.34

    Postprocedural seroma of the spleen following other procedure

  • D78.8

    Other intraoperative and postprocedural complications of the spleen

  • D78.81

    Other intraoperative complications of the spleen

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