Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • D69.5

    Secondary thrombocytopenia

  • D69.51

    Posttransfusion purpura

  • D69.59

    Other secondary thrombocytopenia

  • D69.6

    Thrombocytopenia, unspecified

  • D69.8

    Other specified hemorrhagic conditions

  • D69.9

    Hemorrhagic condition, unspecified

  • D70

    Neutropenia

  • D70.0

    Congenital agranulocytosis

  • D70.1

    Agranulocytosis secondary to cancer chemotherapy

  • D70.2

    Other drug-induced agranulocytosis

  • D70.3

    Neutropenia due to infection

  • D70.4

    Cyclic neutropenia

  • D70.8

    Other neutropenia

  • D70.9

    Neutropenia, unspecified

  • D71

    Functional disorders of polymorphonuclear neutrophils

  • D71.1

    Leukocyte adhesion deficiency

  • D71.8

    Other functional disorders of polymorphonuclear neutrophils

  • D71.9

    Functional disorders of polymorphonuclear neutrophils, unspecified

  • D72

    Other disorders of white blood cells

  • D72.0

    Genetic anomalies of leukocytes

  • D72.1

    Eosinophilia

  • D72.10

    Eosinophilia, unspecified

  • D72.11

    Hypereosinophilic syndrome [HES]

  • D72.110

    Idiopathic hypereosinophilic syndrome [IHES]

  • D72.111

    Lymphocytic Variant Hypereosinophilic Syndrome [LHES]

  • D72.118

    Other hypereosinophilic syndrome

  • D72.119

    Hypereosinophilic syndrome [HES], unspecified

  • D72.12

    Drug rash with eosinophilia and systemic symptoms syndrome

  • D72.18

    Eosinophilia in diseases classified elsewhere

  • D72.19

    Other eosinophilia

  • D72.8

    Other specified disorders of white blood cells

  • D72.81

    Decreased white blood cell count

  • D72.810

    Lymphocytopenia

  • D72.818

    Other decreased white blood cell count

  • D72.819

    Decreased white blood cell count, unspecified

  • D72.82

    Elevated white blood cell count

  • D72.820

    Lymphocytosis (symptomatic)

  • D72.821

    Monocytosis (symptomatic)

  • D72.822

    Plasmacytosis

  • D72.823

    Leukemoid reaction

  • D72.824

    Basophilia

  • D72.825

    Bandemia

  • D72.828

    Other elevated white blood cell count

  • D72.829

    Elevated white blood cell count, unspecified

  • D72.89

    Other specified disorders of white blood cells

  • D72.9

    Disorder of white blood cells, unspecified

  • D73

    Diseases of spleen

  • D73.0

    Hyposplenism

  • D73.1

    Hypersplenism

  • D73.2

    Chronic congestive splenomegaly

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