D56.5

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Hemoglobin E-beta thalassemia

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Excludes1(Not coded here)
  • beta thalassemia (D56.1)
  • beta thalassemia minor (D56.3)
  • beta thalassemia trait (D56.3)
  • delta-beta thalassemia (D56.2)
  • delta-beta thalassemia trait (D56.3)
  • hemoglobin E disease (D58.2)
  • other hemoglobinopathies (D58.2)
  • sickle-cell beta thalassemia (D57.4-)
General instructions are available for the parent sections:
View CH3 NotesView D56 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D56Thalassemia
D56.5Hemoglobin E-beta thalassemia

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D56.5:

categoryD56
Thalassemia
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D56.5. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

3 raw paths
Disease, diseased1 unique routes
hemoglobin or Hb
E-beta thalassemia→D56.5
Hemoglobin1 unique routes
E-beta thalassemia→D56.5
Thalassemia (anemia) (disease)1 unique routes
hemoglobin
E-beta→D56.5

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 791
Prematurity with Major Problems
DRG 793
Full Term Neonate with Major Problems
DRG 811
Red Blood Cell Disorders with MCC
DRG 812
Red Blood Cell Disorders without MCC

Cross Reference

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