D56.3

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Thalassemia minor

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Includes
  • Alpha thalassemia minor
  • Alpha thalassemia silent carrier
  • Alpha thalassemia trait
  • Beta thalassemia minor
  • Beta thalassemia trait
  • Delta-beta thalassemia minor
  • Delta-beta thalassemia trait
  • Thalassemia trait NOS
Excludes1(Not coded here)
  • alpha thalassemia (D56.0)
  • beta thalassemia (D56.1)
  • delta-beta thalassemia (D56.2)
  • hemoglobin E-beta thalassemia (D56.5)
  • sickle-cell trait (D57.3)
General instructions are available for the parent sections:
View CH3 NotesView D56 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D56Thalassemia
D56.3Thalassemia minor

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D56.3:

categoryD56
Thalassemia
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D56.3. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

11 raw paths
Thalassemia (anemia) (disease)9 unique routes
alpha (major) (severe) (triple gene defect)(3 variants)
minor→D56.3
silent carrier→D56.3
trait→D56.3
beta (severe)(2 variants)
minor→D56.3
trait→D56.3
delta-beta (homozygous)(2 variants)
minor→D56.3
trait→D56.3
minor→D56.3
trait→D56.3
Trait (s)2 unique routes
hemoglobin
abnormal NEC
with thalassemia→D56.3
Lepore→D56.3

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 811
Red Blood Cell Disorders with MCC
DRG 812
Red Blood Cell Disorders without MCC

Cross Reference

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