New ICD-10-CM Codes for FY2027

CMS added 190 diagnosis codes in the FY2027 update, effective October 1, 2026. 30 codes were deleted and 4 had their titles revised.

Chapter 2: C00–D49 (Neoplasms)3 codes

C78.31Secondary malignant neoplasm of larynxPreviously C78.39

C78.32Secondary malignant neoplasm of pharynxPreviously C78.39

C79.83Secondary malignant neoplasm of oral cavityPreviously C79.89

Chapter 3: D50–D89 (Diseases of the Blood and Blood-Forming Organs)2 codes

D69.11Glanzmann thrombastheniaPreviously D69.1

D69.19Other qualitative platelet defectsPreviously D69.1

Chapter 4: E00–E89 (Endocrine, Nutritional and Metabolic Diseases)2 codes

E89.830Post bariatric hypoglycemiaPreviously E89.89

E89.838Other postprocedural hypoglycemiaPreviously E89.89

Chapter 5: F01–F99 (Mental, Behavioral and Neurodevelopmental Disorders)1 code

F64.AGender identity disorder, in remissionPreviously F64.9

Chapter 9: I00–I99 (Diseases of the Circulatory System)9 codes

I42.00Dilated cardiomyopathy, unspecifiedPreviously I42.0

I42.01Familial-genetic dilated cardiomyopathyPreviously I42.0

I42.09Other dilated cardiomyopathyPreviously I42.0

I42.81Arrhythmogenic cardiomyopathyPreviously I42.8

I42.89Other cardiomyopathies not elsewhere classifiedPreviously I42.8

I47.22Catecholaminergic polymorphic ventricular tachycardia [CPVT]Previously I47.29

I49.81Brugada syndromePreviously I49.8

I49.82Ventricular bigeminyPreviously I49.8

I49.89Other specified cardiac arrhythmias not elsewhere classifiedPreviously I49.8

Chapter 10: J00–J99 (Diseases of the Respiratory System)6 codes

J34.830Odontogenic sinusitis, maxillary sinusPreviously J34.89

J34.831Odontogenic sinusitis, ethmoid sinusPreviously J34.89

J34.832Odontogenic sinusitis, frontal sinusPreviously J34.89

J34.833Odontogenic sinusitis, sphenoid sinusPreviously J34.89

J34.839Odontogenic sinusitis, unspecifiedPreviously J34.89

J4BPulmonary mycetomaPreviously B47.- and J98.8, B37.1, B38.0, B38.1, B38.2, B44.1

Chapter 11: K00–K95 (Diseases of the Digestive System)6 codes

K31.BHypertrophic pyloric stenosis, in childhoodPreviously Q40.0

K6A.01Prevesical abscessPreviously K68.19

K6A.09Other pelvic abscessPreviously K68.19 and K65.1

K6A.8Other diseases of the pelvis, not elsewhere classifiedPreviously K92.89, N39.8, N50.89, N94.89, R68.89

K74.0AHepatic fibrosis, moderate fibrosisPreviously K74.01

K76.83Intestinal failure-associated liver diseasePreviously K90.83

Chapter 12: L00–L99 (Diseases of the Skin and Subcutaneous Tissue)1 code

L02.237Carbuncle of flankPreviously L02.232

Chapter 13: M00–M99 (Diseases of the Musculoskeletal System and Connective Tissue)31 codes

M04.3VEXAS syndromePreviously M04.8

M67.A01Plantar fasciitis, right footPreviously M72.2

M67.A02Plantar fasciitis, left footPreviously M72.2

M67.A09Plantar fasciitis, unspecified footPreviously M72.2

M72.20Plantar fascial fibromatosis, unspecified footPreviously M72.2

M72.21Plantar fascial fibromatosis, right footPreviously M72.2

M72.22Plantar fascial fibromatosis, left footPreviously M72.2

M86.8X11Other osteomyelitis, right shoulderPreviously M86.8X1

M86.8X12Other osteomyelitis, left shoulderPreviously M86.8X1

M86.8X19Other osteomyelitis, unspecified shoulderPreviously M86.8X1

M86.8X21Other osteomyelitis, right upper armPreviously M86.8X2

M86.8X22Other osteomyelitis, left upper armPreviously M86.8X2

M86.8X29Other osteomyelitis, unspecified upper armPreviously M86.8X2

M86.8X31Other osteomyelitis, right forearmPreviously M86.8X3

M86.8X32Other osteomyelitis, left forearmPreviously M86.8X3

M86.8X39Other osteomyelitis, unspecified forearmPreviously M86.8X3

M86.8X41Other osteomyelitis, right handPreviously M86.8X4

M86.8X42Other osteomyelitis, left handPreviously M86.8X4

M86.8X49Other osteomyelitis, unspecified handPreviously M86.8X4

M86.8X51Other osteomyelitis, right thighPreviously M86.8X5

M86.8X52Other osteomyelitis, left thighPreviously M86.8X5

M86.8X59Other osteomyelitis, unspecified thighPreviously M86.8X5

M86.8X61Other osteomyelitis, right lower legPreviously M86.8X6

M86.8X62Other osteomyelitis, left lower legPreviously M86.8X6

M86.8X69Other osteomyelitis, unspecified lower legPreviously M86.8X6

M86.8X71Other osteomyelitis, right ankle and footPreviously M86.8X7

M86.8X72Other osteomyelitis, left ankle and footPreviously M86.8X7

M86.8X79Other osteomyelitis, unspecified ankle and footPreviously M86.8X7

M86.8X80Other osteomyelitis, skullPreviously M86.8X8

M86.8X81Other osteomyelitis, face and sinusesPreviously M86.8X8

M86.8X89Other osteomyelitis, other sitePreviously M86.8X8

Chapter 14: N00–N99 (Diseases of the Genitourinary System)2 codes

N99.860Intraoperative and postprocedural nipple ischemiaPreviously N99.89

N99.861Intraoperative and postprocedural nipple necrosisPreviously N99.89

Chapter 15: O00–O9A (Pregnancy, Childbirth and the Puerperium)44 codes

O00.121Right interstitial ectopic pregnancy without intrauterine pregnancyPreviously O00.101

O00.122Left interstitial ectopic pregnancy without intrauterine pregnancyPreviously O00.102

O00.129Unspecified interstitial ectopic pregnancy without intrauterine pregnancyPreviously O00.109

O00.131Right interstitial ectopic pregnancy with intrauterine pregnancyPreviously O00.111

O00.132Left interstitial ectopic pregnancy with intrauterine pregnancyPreviously O00.112

O00.139Unspecified interstitial ectopic pregnancy with intrauterine pregnancyPreviously O00.119

O00.31Cesarean scar ectopic pregnancy without intrauterine pregnancyPreviously O00.80

O00.32Cesarean scar ectopic pregnancy with intrauterine pregnancyPreviously O00.81

O00.41Cervical ectopic pregnancy without intrauterine pregnancyPreviously O00.80

O00.42Cervical ectopic pregnancy with intrauterine pregnancyPreviously O00.81

O00.511Right cornual ectopic pregnancy without intrauterine pregnancyPreviously O00.80

O00.512Left cornual ectopic pregnancy without intrauterine pregnancyPreviously O00.80

O00.519Unspecified cornual ectopic pregnancy without intrauterine pregnancyPreviously O00.80

O00.521Right cornual ectopic pregnancy with intrauterine pregnancyPreviously O00.81

O00.522Left cornual ectopic pregnancy with intrauterine pregnancyPreviously O00.81

O00.529Unspecified cornual ectopic pregnancy with intrauterine pregnancyPreviously O00.81

O31.40X0Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, not applicable or unspecifiedPreviously O31.8X90

O31.40X1Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, fetus 1Previously O31.8X91

O31.40X2Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, fetus 2Previously O31.8X92

O31.40X3Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, fetus 3Previously O31.8X93

O31.40X4Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, fetus 4Previously O31.8X94

O31.40X5Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, fetus 5Previously O31.8X95

O31.40X9Continuing pregnancy after vanishing twin syndrome of one fetus or more, unspecified trimester, other fetusPreviously O31.8X99

O31.41X0Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, not applicable or unspecifiedPreviously O31.8X10

O31.41X1Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, fetus 1Previously O31.8X11

O31.41X2Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, fetus 2Previously O31.8X12

O31.41X3Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, fetus 3Previously O31.8X13

O31.41X4Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, fetus 4Previously O31.8X14

O31.41X5Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, fetus 5Previously O31.8X15

O31.41X9Continuing pregnancy after vanishing twin syndrome of one fetus or more, first trimester, other fetusPreviously O31.8X19

O31.42X0Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, not applicable or unspecifiedPreviously O31.8X20

O31.42X1Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, fetus 1Previously O31.8X21

O31.42X2Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, fetus 2Previously O31.8X22

O31.42X3Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, fetus 3Previously O31.8X23

O31.42X4Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, fetus 4Previously O31.8X24

O31.42X5Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, fetus 5Previously O31.8X25

O31.42X9Continuing pregnancy after vanishing twin syndrome of one fetus or more, second trimester, other fetusPreviously O31.8X29

O31.43X0Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, not applicable or unspecifiedPreviously O31.8X30

O31.43X1Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, fetus 1Previously O31.8X31

O31.43X2Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, fetus 2Previously O31.8X32

O31.43X3Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, fetus 3Previously O31.8X33

O31.43X4Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, fetus 4Previously O31.8X34

O31.43X5Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, fetus 5Previously O31.8X35

O31.43X9Continuing pregnancy after vanishing twin syndrome of one fetus or more, third trimester, other fetusPreviously O31.8X39

Chapter 17: Q00–Q99 (Congenital Malformations, Deformations and Chromosomal Abnormalities)6 codes

Q87.ALoeys-Dietz syndromePreviously Q87.89

QA1.71Lynch syndromePreviously Z15.09

QA1.790Familial cancer syndrome with pathogenic BRCA1 mutationPreviously Z15.09

QA1.791Familial cancer syndrome with pathogenic BRCA2 mutationPreviously Z15.09

QA1.792Li Fraumeni syndromePreviously Z15.09

QA1.798Other inherited neoplasm predisposition syndrome of multiple systemsPreviously Z15.09

Chapter 18: R00–R99 (Symptoms, Signs and Abnormal Clinical and Laboratory Findings)1 code

R78.72Abnormal gadolinium level in bloodPreviously R78.79

Chapter 19: S00–T88 (Injury, Poisoning and Certain Other Consequences of External Causes)60 codes

T52.811AToxic effect of alkenes, accidental (unintentional), initial encounterPreviously T52.8X1A

T52.811DToxic effect of alkenes, accidental (unintentional), subsequent encounterPreviously T52.8X1D

T52.811SToxic effect of alkenes, accidental (unintentional), sequelaPreviously T52.8X1S

T52.812AToxic effect of alkenes, intentional self-harm, initial encounterPreviously T52.8X2A

T52.812DToxic effect of alkenes, intentional self-harm, subsequent encounterPreviously T52.8X2D

T52.812SToxic effect of alkenes, intentional self-harm, sequelaPreviously T52.8X2S

T52.813AToxic effect of alkenes, assault, initial encounterPreviously T52.8X3A

T52.813DToxic effect of alkenes, assault, subsequent encounterPreviously T52.8X3D

T52.813SToxic effect of alkenes, assault, sequelaPreviously T52.8X3S

T52.814AToxic effect of alkenes, undetermined, initial encounterPreviously T52.8X4A

T52.814DToxic effect of alkenes, undetermined, subsequent encounterPreviously T52.8X4D

T52.814SToxic effect of alkenes, undetermined, sequelaPreviously T52.8X4S

T52.821AToxic effect of cycloparaffins, accidental (unintentional), initial encounterPreviously T52.8X1A

T52.821DToxic effect of cycloparaffins, accidental (unintentional), subsequent encounterPreviously T52.8X1D

T52.821SToxic effect of cycloparaffins, accidental (unintentional), sequelaPreviously T52.8X1S

T52.822AToxic effect of cycloparaffins, intentional self-harm, initial encounterPreviously T52.8X2A

T52.822DToxic effect of cycloparaffins, intentional self-harm, subsequent encounterPreviously T52.8X2D

T52.822SToxic effect of cycloparaffins, intentional self-harm, sequelaPreviously T52.8X2S

T52.823AToxic effect of cycloparaffins, assault, initial encounterPreviously T52.8X3A

T52.823DToxic effect of cycloparaffins, assault, subsequent encounterPreviously T52.8X3D

T52.823SToxic effect of cycloparaffins, assault, sequelaPreviously T52.8X3S

T52.824AToxic effect of cycloparaffins, undetermined, initial encounterPreviously T52.8X4A

T52.824DToxic effect of cycloparaffins, undetermined, subsequent encounterPreviously T52.8X4D

T52.824SToxic effect of cycloparaffins, undetermined, sequelaPreviously T52.8X4S

T52.891AToxic effect of other organic solvents, accidental (unintentional), initial encounterPreviously T52.8X1A

T52.891DToxic effect of other organic solvents, accidental (unintentional), subsequent encounterPreviously T52.8X1D

T52.891SToxic effect of other organic solvents, accidental (unintentional), sequelaPreviously T52.8X1S

T52.892AToxic effect of other organic solvents, intentional self-harm, initial encounterPreviously T52.8X2A

T52.892DToxic effect of other organic solvents, intentional self-harm, subsequent encounterPreviously T52.8X2D

T52.892SToxic effect of other organic solvents, intentional self-harm, sequelaPreviously T52.8X2S

T52.893AToxic effect of other organic solvents, assault, initial encounterPreviously T52.8X3A

T52.893DToxic effect of other organic solvents, assault, subsequent encounterPreviously T52.8X3D

T52.893SToxic effect of other organic solvents, assault, sequelaPreviously T52.8X3S

T52.894AToxic effect of other organic solvents, undetermined, initial encounterPreviously T52.8X4A

T52.894DToxic effect of other organic solvents, undetermined, subsequent encounterPreviously T52.8X4D

T52.894SToxic effect of other organic solvents, undetermined, sequelaPreviously T52.8X4S

T59.821AToxic effect of hexamethylene diisocyanate, accidental (unintentional), initial encounterPreviously T59.891A

T59.821DToxic effect of hexamethylene diisocyanate, accidental (unintentional), subsequent encounterPreviously T59.891D

T59.821SToxic effect of hexamethylene diisocyanate, accidental (unintentional), sequelaPreviously T59.891S

T59.822AToxic effect of hexamethylene diisocyanate, intentional self-harm, initial encounterPreviously T59.892A

T59.822DToxic effect of hexamethylene diisocyanate, intentional self-harm, subsequent encounterPreviously T59.892D

T59.822SToxic effect of hexamethylene diisocyanate, intentional self-harm, sequelaPreviously T59.892S

T59.823AToxic effect of hexamethylene diisocyanate, assault, initial encounterPreviously T59.893A

T59.823DToxic effect of hexamethylene diisocyanate, assault, subsequent encounterPreviously T59.893D

T59.823SToxic effect of hexamethylene diisocyanate, assault, sequelaPreviously T59.893S

T59.824AToxic effect of hexamethylene diisocyanate, undetermined, initial encounterPreviously T59.894A

T59.824DToxic effect of hexamethylene diisocyanate, undetermined, subsequent encounterPreviously T59.894D

T59.824SToxic effect of hexamethylene diisocyanate, undetermined, sequelaPreviously T59.894S

T65.851AToxic effect of medetomidine, accidental (unintentional), initial encounterPreviously T65.891A

T65.851DToxic effect of medetomidine, accidental (unintentional), subsequent encounterPreviously T65.891D

T65.851SToxic effect of medetomidine, accidental (unintentional), sequelaPreviously T65.891S

T65.852AToxic effect of medetomidine, intentional self-harm, initial encounterPreviously T65.892A

T65.852DToxic effect of medetomidine, intentional self-harm, subsequent encounterPreviously T65.892D

T65.852SToxic effect of medetomidine, intentional self-harm, sequelaPreviously T65.892S

T65.853AToxic effect of medetomidine, assault, initial encounterPreviously T65.893A

T65.853DToxic effect of medetomidine, assault, subsequent encounterPreviously T65.893D

T65.853SToxic effect of medetomidine, assault, sequelaPreviously T65.893S

T65.854AToxic effect of medetomidine, undetermined, initial encounterPreviously T65.894A

T65.854DToxic effect of medetomidine, undetermined, subsequent encounterPreviously T65.894D

T65.854SToxic effect of medetomidine, undetermined, sequelaPreviously T65.894S

Chapter 21: Z00–Z99 (Factors Influencing Health Status and Contact with Health Services)16 codes

Z68.18Body mass index [BMI] 18.4 or less, adultPreviously Z68.1

Z68.19Body mass index [BMI] 18.5-19.9, adultPreviously Z68.1

Z77.013Contact with and (suspected) exposure to gadoliniumPreviously Z77.018

Z77.32Contact with and (suspected) exposure to burn pits in war theaterPreviously Z77.39

Z77.33Contact with and (suspected) exposure to Agent OrangePreviously Z77.39

Z77.40Contact with and (suspected) exposure to unspecified blast overpressurePreviously Z77.9

Z77.41Contact with and (suspected) exposure to low-level blast overpressurePreviously Z77.9

Z77.42Contact with and (suspected) exposure to high-level blast overpressurePreviously Z77.9

Z77.49Contact with and (suspected) exposure to other blast overpressurePreviously Z77.9

Z86.17Personal history of Clostridioides difficile infectionPreviously Z86.19

Z87.8901Personal history of social gender transitionPreviously Z87.890

Z87.8902Personal history of medical gender transitionPreviously Z87.890

Z87.8903Personal history of surgical gender transitionPreviously Z87.890

Z87.8904Personal history of intersex surgeryPreviously Z87.890

Z87.8909Personal history of unspecified gender transitionPreviously Z87.890

Z87.893Personal history of gender detransitionPreviously Z87.898

Deleted codes (30)

These codes are invalid for discharges on or after October 1, 2026. Use the new, more specific code instead.

D69.1Qualitative platelet defectsNow D69.11, D69.19

I42.0Dilated cardiomyopathyNow I42.00, I42.01, I42.09

I42.8Other cardiomyopathiesNow I42.81, I42.89

I49.8Other specified cardiac arrhythmiasNow I49.81, I49.82, I49.89

M72.2Plantar fascial fibromatosisNow M67.A01, M67.A02, M67.A09, M72.20, M72.21, M72.22

M86.8X1Other osteomyelitis, shoulderNow M86.8X11, M86.8X12, M86.8X19

M86.8X2Other osteomyelitis, upper armNow M86.8X21, M86.8X22, M86.8X29

M86.8X3Other osteomyelitis, forearmNow M86.8X31, M86.8X32, M86.8X39

M86.8X4Other osteomyelitis, handNow M86.8X41, M86.8X42, M86.8X49

M86.8X5Other osteomyelitis, thighNow M86.8X51, M86.8X52, M86.8X59

M86.8X6Other osteomyelitis, lower legNow M86.8X61, M86.8X62, M86.8X69

M86.8X7Other osteomyelitis, ankle and footNow M86.8X71, M86.8X72, M86.8X79

M86.8X8Other osteomyelitis, other siteNow M86.8X80, M86.8X81, M86.8X89

S23.420ASprain of sternoclavicular (joint) (ligament), initial encounter

S23.420DSprain of sternoclavicular (joint) (ligament), subsequent encounter

S23.420SSprain of sternoclavicular (joint) (ligament), sequela

T52.8X1AToxic effect of other organic solvents, accidental (unintentional), initial encounterNow T52.811A, T52.821A, T52.891A

T52.8X1DToxic effect of other organic solvents, accidental (unintentional), subsequent encounterNow T52.811D, T52.821D, T52.891D

T52.8X1SToxic effect of other organic solvents, accidental (unintentional), sequelaNow T52.811S, T52.821S, T52.891S

T52.8X2AToxic effect of other organic solvents, intentional self-harm, initial encounterNow T52.812A, T52.822A, T52.892A

T52.8X2DToxic effect of other organic solvents, intentional self-harm, subsequent encounterNow T52.812D, T52.822D, T52.892D

T52.8X2SToxic effect of other organic solvents, intentional self-harm, sequelaNow T52.812S, T52.822S, T52.892S

T52.8X3AToxic effect of other organic solvents, assault, initial encounterNow T52.813A, T52.823A, T52.893A

T52.8X3DToxic effect of other organic solvents, assault, subsequent encounterNow T52.813D, T52.823D, T52.893D

T52.8X3SToxic effect of other organic solvents, assault, sequelaNow T52.813S, T52.823S, T52.893S

T52.8X4AToxic effect of other organic solvents, undetermined, initial encounterNow T52.814A, T52.824A, T52.894A

T52.8X4DToxic effect of other organic solvents, undetermined, subsequent encounterNow T52.814D, T52.824D, T52.894D

T52.8X4SToxic effect of other organic solvents, undetermined, sequelaNow T52.814S, T52.824S, T52.894S

Z68.1Body mass index [BMI] 19.9 or less, adultNow Z68.18, Z68.19

Z87.890Personal history of sex reassignmentNow Z87.8901, Z87.8902, Z87.8903, Z87.8904, Z87.8909

Revised titles (4)

L02.232

Carbuncle of back [any part, except buttock and flank]

Carbuncle of back [any part, except buttock]

L03.312

Cellulitis of back [any part except buttock and flank]

Cellulitis of back [any part except buttock]

L03.322

Acute lymphangitis of back [any part except buttock and flank]

Acute lymphangitis of back [any part except buttock]

Z29.14

Encounter for prophylactic rabies immune globulin

Encounter for prophylactic rabies immune globin