Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R40.2344|

    Coma scale, best motor response, flexion withdrawal, 24 hours or more after hospital admission

  • R40.235|

    Coma scale, best motor response, localizes pain

  • R40.2350|

    Coma scale, best motor response, localizes pain, unspecified time

  • R40.2351|

    Coma scale, best motor response, localizes pain, in the field [EMT or ambulance]

  • R40.2352|

    Coma scale, best motor response, localizes pain, at arrival to emergency department

  • R40.2353|

    Coma scale, best motor response, localizes pain, at hospital admission

  • R40.2354|

    Coma scale, best motor response, localizes pain, 24 hours or more after hospital admission

  • R40.236|

    Coma scale, best motor response, obeys commands

  • R40.2360|

    Coma scale, best motor response, obeys commands, unspecified time

  • R40.2361|

    Coma scale, best motor response, obeys commands, in the field [EMT or ambulance]

  • R40.2362|

    Coma scale, best motor response, obeys commands, at arrival to emergency department

  • R40.2363|

    Coma scale, best motor response, obeys commands, at hospital admission

  • R40.2364|

    Coma scale, best motor response, obeys commands, 24 hours or more after hospital admission

  • R40.24|

    Glasgow coma scale, total score

  • R40.241|

    Glasgow coma scale score 13-15

  • R40.2410|

    Glasgow coma scale score 13-15, unspecified time

  • R40.2411|

    Glasgow coma scale score 13-15, in the field [EMT or ambulance]

  • R40.2412|

    Glasgow coma scale score 13-15, at arrival to emergency department

  • R40.2413|

    Glasgow coma scale score 13-15, at hospital admission

  • R40.2414|

    Glasgow coma scale score 13-15, 24 hours or more after hospital admission

  • R40.242|

    Glasgow coma scale score 9-12

  • R40.2420|

    Glasgow coma scale score 9-12, unspecified time

  • R40.2421|

    Glasgow coma scale score 9-12, in the field [EMT or ambulance]

  • R40.2422|

    Glasgow coma scale score 9-12, at arrival to emergency department

  • R40.2423|

    Glasgow coma scale score 9-12, at hospital admission

  • R40.2424|

    Glasgow coma scale score 9-12, 24 hours or more after hospital admission

  • R40.243|

    Glasgow coma scale score 3-8

  • R40.2430|

    Glasgow coma scale score 3-8, unspecified time

  • R40.2431|

    Glasgow coma scale score 3-8, in the field [EMT or ambulance]

  • R40.2432|

    Glasgow coma scale score 3-8, at arrival to emergency department

  • R40.2433|

    Glasgow coma scale score 3-8, at hospital admission

  • R40.2434|

    Glasgow coma scale score 3-8, 24 hours or more after hospital admission

  • R40.244|

    Other coma, without documented Glasgow coma scale score, or with partial score reported

  • R40.2440|

    Other coma, without documented Glasgow coma scale score, or with partial score reported, unspecified time

  • R40.2441|

    Other coma, without documented Glasgow coma scale score, or with partial score reported, in the field [EMT or ambulance]

  • R40.2442|

    Other coma, without documented Glasgow coma scale score, or with partial score reported, at arrival to emergency department

  • R40.2443|

    Other coma, without documented Glasgow coma scale score, or with partial score reported, at hospital admission

  • R40.2444|

    Other coma, without documented Glasgow coma scale score, or with partial score reported, 24 hours or more after hospital admission

  • R40.2A|

    Nontraumatic coma due to underlying condition

  • R40.3|

    Persistent vegetative state

  • R40.4|

    Transient alteration of awareness

  • R41|

    Other symptoms and signs involving cognitive functions and awareness

  • R41.0|

    Disorientation, unspecified

  • R41.1|

    Anterograde amnesia

  • R41.2|

    Retrograde amnesia

  • R41.3|

    Other amnesia

  • R41.4|

    Neurologic neglect syndrome

  • R41.8|

    Other symptoms and signs involving cognitive functions and awareness

  • R41.81|

    Age-related cognitive decline

  • R41.82|

    Altered mental status, unspecified

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