Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R41.83|

    Borderline intellectual functioning

  • R41.84|

    Other specified cognitive deficit

  • R41.840|

    Attention and concentration deficit

  • R41.841|

    Cognitive communication deficit

  • R41.842|

    Visuospatial deficit

  • R41.843|

    Psychomotor deficit

  • R41.844|

    Frontal lobe and executive function deficit

  • R41.85|

    Anosognosia

  • R41.89|

    Other symptoms and signs involving cognitive functions and awareness

  • R41.9|

    Unspecified symptoms and signs involving cognitive functions and awareness

  • R42|

    Dizziness and giddiness

  • R43|

    Disturbances of smell and taste

  • R43.0|

    Anosmia

  • R43.1|

    Parosmia

  • R43.2|

    Parageusia

  • R43.8|

    Other disturbances of smell and taste

  • R43.9|

    Unspecified disturbances of smell and taste

  • R44|

    Other symptoms and signs involving general sensations and perceptions

  • R44.0|

    Auditory hallucinations

  • R44.1|

    Visual hallucinations

  • R44.2|

    Other hallucinations

  • R44.3|

    Hallucinations, unspecified

  • R44.8|

    Other symptoms and signs involving general sensations and perceptions

  • R44.9|

    Unspecified symptoms and signs involving general sensations and perceptions

  • R45|

    Symptoms and signs involving emotional state

  • R45.0|

    Nervousness

  • R45.1|

    Restlessness and agitation

  • R45.2|

    Unhappiness

  • R45.3|

    Demoralization and apathy

  • R45.4|

    Irritability and anger

  • R45.5|

    Hostility

  • R45.6|

    Violent behavior

  • R45.7|

    State of emotional shock and stress, unspecified

  • R45.8|

    Other symptoms and signs involving emotional state

  • R45.81|

    Low self-esteem

  • R45.82|

    Worries

  • R45.83|

    Excessive crying of child, adolescent or adult

  • R45.84|

    Anhedonia

  • R45.85|

    Homicidal and suicidal ideations

  • R45.850|

    Homicidal ideations

  • R45.851|

    Suicidal ideations

  • R45.86|

    Emotional lability

  • R45.87|

    Impulsiveness

  • R45.88|

    Nonsuicidal self-harm

  • R45.89|

    Other symptoms and signs involving emotional state

  • R46|

    Symptoms and signs involving appearance and behavior

  • R46.0|

    Very low level of personal hygiene

  • R46.1|

    Bizarre personal appearance

  • R46.2|

    Strange and inexplicable behavior

  • R46.3|

    Overactivity

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