Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R41.83

    Borderline intellectual functioning

  • R41.84

    Other specified cognitive deficit

  • R41.840

    Attention and concentration deficit

  • R41.841

    Cognitive communication deficit

  • R41.842

    Visuospatial deficit

  • R41.843

    Psychomotor deficit

  • R41.844

    Frontal lobe and executive function deficit

  • R41.85

    Anosognosia

  • R41.89

    Other symptoms and signs involving cognitive functions and awareness

  • R41.9

    Unspecified symptoms and signs involving cognitive functions and awareness

  • R42

    Dizziness and giddiness

  • R43

    Disturbances of smell and taste

  • R43.0

    Anosmia

  • R43.1

    Parosmia

  • R43.2

    Parageusia

  • R43.8

    Other disturbances of smell and taste

  • R43.9

    Unspecified disturbances of smell and taste

  • R44

    Other symptoms and signs involving general sensations and perceptions

  • R44.0

    Auditory hallucinations

  • R44.1

    Visual hallucinations

  • R44.2

    Other hallucinations

  • R44.3

    Hallucinations, unspecified

  • R44.8

    Other symptoms and signs involving general sensations and perceptions

  • R44.9

    Unspecified symptoms and signs involving general sensations and perceptions

  • R45

    Symptoms and signs involving emotional state

  • R45.0

    Nervousness

  • R45.1

    Restlessness and agitation

  • R45.2

    Unhappiness

  • R45.3

    Demoralization and apathy

  • R45.4

    Irritability and anger

  • R45.5

    Hostility

  • R45.6

    Violent behavior

  • R45.7

    State of emotional shock and stress, unspecified

  • R45.8

    Other symptoms and signs involving emotional state

  • R45.81

    Low self-esteem

  • R45.82

    Worries

  • R45.83

    Excessive crying of child, adolescent or adult

  • R45.84

    Anhedonia

  • R45.85

    Homicidal and suicidal ideations

  • R45.850

    Homicidal ideations

  • R45.851

    Suicidal ideations

  • R45.86

    Emotional lability

  • R45.87

    Impulsiveness

  • R45.88

    Nonsuicidal self-harm

  • R45.89

    Other symptoms and signs involving emotional state

  • R46

    Symptoms and signs involving appearance and behavior

  • R46.0

    Very low level of personal hygiene

  • R46.1

    Bizarre personal appearance

  • R46.2

    Strange and inexplicable behavior

  • R46.3

    Overactivity

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