Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R40.2213

    Coma scale, best verbal response, none, at hospital admission

  • R40.2214

    Coma scale, best verbal response, none, 24 hours or more after hospital admission

  • R40.222

    Coma scale, best verbal response, incomprehensible words

  • R40.2220

    Coma scale, best verbal response, incomprehensible words, unspecified time

  • R40.2221

    Coma scale, best verbal response, incomprehensible words, in the field [EMT or ambulance]

  • R40.2222

    Coma scale, best verbal response, incomprehensible words, at arrival to emergency department

  • R40.2223

    Coma scale, best verbal response, incomprehensible words, at hospital admission

  • R40.2224

    Coma scale, best verbal response, incomprehensible words, 24 hours or more after hospital admission

  • R40.223

    Coma scale, best verbal response, inappropriate words

  • R40.2230

    Coma scale, best verbal response, inappropriate words, unspecified time

  • R40.2231

    Coma scale, best verbal response, inappropriate words, in the field [EMT or ambulance]

  • R40.2232

    Coma scale, best verbal response, inappropriate words, at arrival to emergency department

  • R40.2233

    Coma scale, best verbal response, inappropriate words, at hospital admission

  • R40.2234

    Coma scale, best verbal response, inappropriate words, 24 hours or more after hospital admission

  • R40.224

    Coma scale, best verbal response, confused conversation

  • R40.2240

    Coma scale, best verbal response, confused conversation, unspecified time

  • R40.2241

    Coma scale, best verbal response, confused conversation, in the field [EMT or ambulance]

  • R40.2242

    Coma scale, best verbal response, confused conversation, at arrival to emergency department

  • R40.2243

    Coma scale, best verbal response, confused conversation, at hospital admission

  • R40.2244

    Coma scale, best verbal response, confused conversation, 24 hours or more after hospital admission

  • R40.225

    Coma scale, best verbal response, oriented

  • R40.2250

    Coma scale, best verbal response, oriented, unspecified time

  • R40.2251

    Coma scale, best verbal response, oriented, in the field [EMT or ambulance]

  • R40.2252

    Coma scale, best verbal response, oriented, at arrival to emergency department

  • R40.2253

    Coma scale, best verbal response, oriented, at hospital admission

  • R40.2254

    Coma scale, best verbal response, oriented, 24 hours or more after hospital admission

  • R40.23

    Coma scale, best motor response

  • R40.231

    Coma scale, best motor response, none

  • R40.2310

    Coma scale, best motor response, none, unspecified time

  • R40.2311

    Coma scale, best motor response, none, in the field [EMT or ambulance]

  • R40.2312

    Coma scale, best motor response, none, at arrival to emergency department

  • R40.2313

    Coma scale, best motor response, none, at hospital admission

  • R40.2314

    Coma scale, best motor response, none, 24 hours or more after hospital admission

  • R40.232

    Coma scale, best motor response, extension

  • R40.2320

    Coma scale, best motor response, extension, unspecified time

  • R40.2321

    Coma scale, best motor response, extension, in the field [EMT or ambulance]

  • R40.2322

    Coma scale, best motor response, extension, at arrival to emergency department

  • R40.2323

    Coma scale, best motor response, extension, at hospital admission

  • R40.2324

    Coma scale, best motor response, extension, 24 hours or more after hospital admission

  • R40.233

    Coma scale, best motor response, abnormal flexion

  • R40.2330

    Coma scale, best motor response, abnormal flexion, unspecified time

  • R40.2331

    Coma scale, best motor response, abnormal flexion, in the field [EMT or ambulance]

  • R40.2332

    Coma scale, best motor response, abnormal flexion, at arrival to emergency department

  • R40.2333

    Coma scale, best motor response, abnormal flexion, at hospital admission

  • R40.2334

    Coma scale, best motor response, abnormal flexion, 24 hours or more after hospital admission

  • R40.234

    Coma scale, best motor response, flexion withdrawal

  • R40.2340

    Coma scale, best motor response, flexion withdrawal, unspecified time

  • R40.2341

    Coma scale, best motor response, flexion withdrawal, in the field [EMT or ambulance]

  • R40.2342

    Coma scale, best motor response, flexion withdrawal, at arrival to emergency department

  • R40.2343

    Coma scale, best motor response, flexion withdrawal, at hospital admission

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