R50-R69Not billable, use a more specific code below
General symptoms and signs (R50-R69)
chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings
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Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Covers when to report symptom, sign, and abnormal finding codes (R00-R99), plus specific rules for falls, coma scales, non-infectious SIRS, death NOS, and NIHSS scores.
- Use of symptom codes (page 75)
- Use of a symptom code with a definitive diagnosis code (page 75)
- Combination codes that include symptoms (page 75)
- Repeated falls (page 76)
- Coma (page 76)
- Functional quadriplegia (page 76)
- SIRS due to Non-Infectious Process (page 77)
- Death NOS (page 77)
All codes under R50-R69
R50-R69 can't be used on a claim. Pick a billable code below; grey headings group them.
- R50Fever of other and unknown origin
- R50.2Drug induced fever
- R50.8Other specified fever
- R50.81Fever presenting with conditions classified elsewhere
- R50.82Postprocedural fever
- R50.83Postvaccination fever
- R50.84Febrile nonhemolytic transfusion reaction
- R50.9Fever, unspecified
- R51Headache
- R51.0Headache with orthostatic component, not elsewhere classified
- R51.9Headache, unspecified
- R52Pain, unspecified
- R53Malaise and fatigue
- R53.0Neoplastic (malignant) related fatigue
- R53.1Weakness
- R53.2Functional quadriplegia
- R53.8Other malaise and fatigue
- R53.81Other malaise
- R53.82Chronic fatigue, unspecified
- R53.83Other fatigue
- R54Age-related physical debility
- R55Syncope and collapse
- R56Convulsions, not elsewhere classified
- R56.0Febrile convulsions
- R56.00Simple febrile convulsions
- R56.01Complex febrile convulsions
- R56.1Post traumatic seizures
- R56.9Unspecified convulsions
- R57Shock, not elsewhere classified
- R57.0Cardiogenic shock
- R57.1Hypovolemic shock
- R57.8Other shock
- R57.9Shock, unspecified
- R58Hemorrhage, not elsewhere classified
- R59Enlarged lymph nodes
- R59.0Localized enlarged lymph nodes
- R59.1Generalized enlarged lymph nodes
- R59.9Enlarged lymph nodes, unspecified
- R60Edema, not elsewhere classified
- R60.0Localized edema
- R60.1Generalized edema
- R60.9Edema, unspecified
- R61Generalized hyperhidrosis
- R62Lack of expected normal physiological development in childhood and adults
- R62.0Delayed milestone in childhood
- R62.5Other and unspecified lack of expected normal physiological development in childhood
- R62.50Unspecified lack of expected normal physiological development in childhood
- R62.51Failure to thrive (child)
- R62.52Short stature (child)
- R62.59Other lack of expected normal physiological development in childhood
- R62.7Adult failure to thrive
- R63Symptoms and signs concerning food and fluid intake
- R63.0Anorexia
- R63.1Polydipsia
- R63.2Polyphagia
- R63.3Feeding difficulties
- R63.30Feeding difficulties, unspecified
- R63.31Pediatric feeding disorder, acute
- R63.32Pediatric feeding disorder, chronic
- R63.39Other feeding difficulties
- R63.4Abnormal weight loss
- R63.5Abnormal weight gain
- R63.6Underweight
- R63.8Other symptoms and signs concerning food and fluid intake
- R64Cachexia
- R65Symptoms and signs specifically associated with systemic inflammation and infection
- R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious origin
- R65.10Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
- R65.11Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
- R65.2Severe sepsis
- R65.20Severe sepsis without septic shock
- R65.21Severe sepsis with septic shock
- R68Other general symptoms and signs
- R68.0Hypothermia, not associated with low environmental temperature
- R68.1Nonspecific symptoms peculiar to infancy
- R68.11Excessive crying of infant (baby)
- R68.12Fussy infant (baby)
- R68.13Apparent life threatening event in infant (ALTE)
- R68.19Other nonspecific symptoms peculiar to infancy
- R68.2Dry mouth, unspecified
- R68.3Clubbing of fingers
- R68.8Other general symptoms and signs
- R68.81Early satiety
- R68.82Decreased libido
- R68.83Chills (without fever)
- R68.84Jaw pain
- R68.89Other general symptoms and signs
- R69Illness, unspecified
R50-R69 MS-DRGs
This code does not group to an MS-DRG as a principal diagnosis.
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Fever
A fever is a body temperature that is higher than normal. A normal temperature can vary from person to person, but it is usually around 98.6 °F (37 °C). A fever is not a disease. It is usually a sign that your body is trying to fight an illness or infection.
Read more about fever on MedlinePlus