All ICD10 Codes

R65.1

Non-Billable
ChapterR00–R99
Ranksubcategory
Official Description

Systemic inflammatory response syndrome (SIRS) of non-infectious origin

Use a more specific code (2 billable)
R65.10Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunctionR65.11Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
Metadata & Insights
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings (R00-R99).

Instructional Notes

Excludes1(Not coded here. Use a different code.)
  • sepsis- code to infection
  • severe sepsis (R65.2)
Code First
  • underlying condition, such as:
  • heatstroke (T67.0-)
  • injury and trauma (S00-T88)
General instructions are available for the parent sections:
View CH18 Notes

Clinical Hierarchy

BillableHas subcodes
CH18Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
R50-R69General symptoms and signs (R50-R69)
R65Symptoms and signs specifically associated with systemic inflammation and infection
R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious originNot billable
R65.10Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunctionBillable
R65.11Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunctionBillable

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to R65.1:

chapterCH18
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
View context instructions

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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