Chapter 4

E00–E89: Endocrine, Nutritional and Metabolic Diseases

Endocrine, Nutritional and Metabolic Diseases diagnostic classification updated for 2026.

Chapter Instructions

Excludes1(Not coded here. Use a different code.)
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Internal Codes
  • E88.10

    Lipodystrophy, unspecified

  • E88.11

    Partial lipodystrophy

  • E88.12

    Generalized lipodystrophy

  • E88.13

    Localized lipodystrophy

  • E88.14

    HIV-associated lipodystrophy

  • E88.19

    Other lipodystrophy, not elsewhere classified

  • E88.2

    Lipomatosis, not elsewhere classified

  • E88.3

    Tumor lysis syndrome

  • E88.40

    Mitochondrial metabolism disorder, unspecified

  • E88.41

    MELAS syndrome

  • E88.42

    MERRF syndrome

  • E88.43

    Disorders of mitochondrial tRNA synthetases

  • E88.49

    Other mitochondrial metabolism disorders

  • E88.810

    Metabolic syndrome

  • E88.811

    Insulin resistance syndrome, Type A

  • E88.818

    Other insulin resistance

  • E88.819

    Insulin resistance, unspecified

  • E88.82

    Obesity due to disruption of MC4R pathway

  • E88.89

    Other specified metabolic disorders

  • E88.9

    Metabolic disorder, unspecified

  • E88.A

    Wasting disease (syndrome) due to underlying condition

  • E89.0

    Postprocedural hypothyroidism

  • E89.1

    Postprocedural hypoinsulinemia

  • E89.2

    Postprocedural hypoparathyroidism

  • E89.3

    Postprocedural hypopituitarism

  • E89.40

    Asymptomatic postprocedural ovarian failure

  • E89.41

    Symptomatic postprocedural ovarian failure

  • E89.5

    Postprocedural testicular hypofunction

  • E89.6

    Postprocedural adrenocortical (-medullary) hypofunction

  • E89.810

    Postprocedural hemorrhage of an endocrine system organ or structure following an endocrine system procedure

  • E89.811

    Postprocedural hemorrhage of an endocrine system organ or structure following other procedure

  • E89.820

    Postprocedural hematoma of an endocrine system organ or structure following an endocrine system procedure

  • E89.821

    Postprocedural hematoma of an endocrine system organ or structure following other procedure

  • E89.822

    Postprocedural seroma of an endocrine system organ or structure following an endocrine system procedure

  • E89.823

    Postprocedural seroma of an endocrine system organ or structure following other procedure

  • E89.89

    Other postprocedural endocrine and metabolic complications and disorders

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