E85

Non-Billable
ChapterE00–E89
Rankcategory
Official Description

Amyloidosis

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89).

CH4 Parent Instructions

Excludes1(Not coded here)
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

E70-E88 Parent Instructions

Excludes1(Not coded here)
  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
Excludes2(Not included here)
  • Ehlers-Danlos syndromes (Q79.6-)

Instructional Notes

Excludes2(Not included here)
  • Alzheimer's disease (G30.0-)

Clinical Hierarchy

CH4Endocrine, nutritional and metabolic diseases (E00-E89)
E70-E88Metabolic disorders (E70-E88)
E85Amyloidosis
E85.0Non-neuropathic heredofamilial amyloidosis
E85.1Neuropathic heredofamilial amyloidosis
E85.2Heredofamilial amyloidosis, unspecified
E85.3Secondary systemic amyloidosis
E85.4Organ-limited amyloidosis
E85.8Other amyloidosis
E85.9Amyloidosis, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to E85:

blockE70-E88
Metabolic disorders (E70-E88)
View context instructions
chapterCH4
Endocrine, nutritional and metabolic diseases (E00-E89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to E85. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Amyloid heart (disease)1 unique routes
Direct index entry→E85
Amyloidosis (generalized) (primary)20 unique routes
Direct index entry→E85
familial→E85
genetic→E85
heart→E85
hemodialysis-associated→E85
light chain (AL)→E85
liver→E85
localized→E85
neuropathic heredofamilial→E85
non-neuropathic heredofamilial→E85
organ limited→E85
Portuguese→E85
pulmonary→E85
secondary systemic→E85
senile systemic (SSA)→E85
skin (lichen) (macular)→E85
specified NEC→E85
subglottic→E85
wild-type transthyretin-related (ATTR)→E85
with lung involvement→E85
Angiopathia, angiopathy1 unique routes
cerebral
amyloid→E85
Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute)1 unique routes
in (due to)
amyloidosis→E85
Arthropathy1 unique routes
in (due to)
amyloidosis→E85
Cardiomyopathy (familial) (idiopathic)1 unique routes
amyloid→E85

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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