D55

Non-Billable
ChapterD50–D89
Rankcategory
Official Description

Anemia due to enzyme disorders

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Instructional Notes

Excludes1(Not coded here)
  • drug-induced enzyme deficiency anemia (D59.2)

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D55Anemia due to enzyme disorders
D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
D55.1Anemia due to other disorders of glutathione metabolism
D55.2Anemia due to disorders of glycolytic enzymes
D55.3Anemia due to disorders of nucleotide metabolism
D55.8Other anemias due to enzyme disorders
D55.9Anemia due to enzyme disorder, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D55:

chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D55. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)25 unique routes
Baghdad spring→D55
deficiency(23 variants)
2, 3 diphosphoglycurate mutase→D55
2, 3 PG→D55
6 phosphogluconate dehydrogenase→D55
6-PGD→D55
enzyme→D55(6 variants)
glucose-6-phosphate dehydrogenase (G6PD)→D55
glycolytic→D55
nucleotide metabolism→D55
related to hexose monophosphate (HMP) shunt pathway NEC→D55
specified type NEC→D55
erythrocytic glutathione→D55
G SH→D55
G6PD→D55
GGS-R→D55
glucose-6-phosphate dehydrogenase→D55
glutathione reductase→D55
glyceraldehyde phosphate dehydrogenase→D55
hexokinase→D55
phosphofructo-aldolase→D55
phosphoglycerate kinase→D55
PK→D55
pyruvate kinase→D55
triose-phosphate isomerase→D55
due to (in) (with)
disorder of
glutathione metabolism→D55

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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