D55.2

Non-Billable
ChapterD50–D89
Ranksubcategory
Official Description

Anemia due to disorders of glycolytic enzymes

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Excludes1(Not coded here)
  • disorders of glycolysis not associated with anemia (E74.81-)
General instructions are available for the parent sections:
View CH3 NotesView D55 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D55Anemia due to enzyme disorders
D55.2Anemia due to disorders of glycolytic enzymes
D55.21Anemia due to pyruvate kinase deficiency
D55.29Anemia due to other disorders of glycolytic enzymes

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D55.2:

categoryD55
Anemia due to enzyme disorders
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D55.2. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

17 raw paths
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)16 unique routes
deficiency(10 variants)
2, 3 diphosphoglycurate mutase→D55.2
2, 3 PG→D55.2
enzyme
glycolytic→D55.2
glyceraldehyde phosphate dehydrogenase→D55.2
hexokinase→D55.2
phosphofructo-aldolase→D55.2
phosphoglycerate kinase→D55.2
PK→D55.2
pyruvate kinase→D55.2
triose-phosphate isomerase→D55.2
hemolytic(3 variants)
nonspherocytic(3 variants)
congenital or hereditary NEC(2 variants)
pyruvate kinase deficiency→D55.2
type
II→D55.2
type
II→D55.2
hexokinase deficiency→D55.2
pyruvate kinase deficiency→D55.2
with (due to) (in)
disorder of
anaerobic glycolysis→D55.2
Disorder (of)1 unique routes
anaerobic glycolysis with anemia→D55.2

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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