Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R85.7|

    Abnormal histological findings in specimens from digestive organs and abdominal cavity

  • R85.8|

    Other abnormal findings in specimens from digestive organs and abdominal cavity

  • R85.81|

    Anal high risk human papillomavirus (HPV) DNA test positive

  • R85.82|

    Anal low risk human papillomavirus (HPV) DNA test positive

  • R85.89|

    Other abnormal findings in specimens from digestive organs and abdominal cavity

  • R85.9|

    Unspecified abnormal finding in specimens from digestive organs and abdominal cavity

  • R86|

    Abnormal findings in specimens from male genital organs

  • R86.0|

    Abnormal level of enzymes in specimens from male genital organs

  • R86.1|

    Abnormal level of hormones in specimens from male genital organs

  • R86.2|

    Abnormal level of other drugs, medicaments and biological substances in specimens from male genital organs

  • R86.3|

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from male genital organs

  • R86.4|

    Abnormal immunological findings in specimens from male genital organs

  • R86.5|

    Abnormal microbiological findings in specimens from male genital organs

  • R86.6|

    Abnormal cytological findings in specimens from male genital organs

  • R86.7|

    Abnormal histological findings in specimens from male genital organs

  • R86.8|

    Other abnormal findings in specimens from male genital organs

  • R86.9|

    Unspecified abnormal finding in specimens from male genital organs

  • R87|

    Abnormal findings in specimens from female genital organs

  • R87.0|

    Abnormal level of enzymes in specimens from female genital organs

  • R87.1|

    Abnormal level of hormones in specimens from female genital organs

  • R87.2|

    Abnormal level of other drugs, medicaments and biological substances in specimens from female genital organs

  • R87.3|

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from female genital organs

  • R87.4|

    Abnormal immunological findings in specimens from female genital organs

  • R87.5|

    Abnormal microbiological findings in specimens from female genital organs

  • R87.6|

    Abnormal cytological findings in specimens from female genital organs

  • R87.61|

    Abnormal cytological findings in specimens from cervix uteri

  • R87.610|

    Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)

  • R87.611|

    Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)

  • R87.612|

    Low grade squamous intraepithelial lesion on cytologic smear of cervix (LGSIL)

  • R87.613|

    High grade squamous intraepithelial lesion on cytologic smear of cervix (HGSIL)

  • R87.614|

    Cytologic evidence of malignancy on smear of cervix

  • R87.615|

    Unsatisfactory cytologic smear of cervix

  • R87.616|

    Satisfactory cervical smear but lacking transformation zone

  • R87.618|

    Other abnormal cytological findings on specimens from cervix uteri

  • R87.619|

    Unspecified abnormal cytological findings in specimens from cervix uteri

  • R87.62|

    Abnormal cytological findings in specimens from vagina

  • R87.620|

    Atypical squamous cells of undetermined significance on cytologic smear of vagina (ASC-US)

  • R87.621|

    Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H)

  • R87.622|

    Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)

  • R87.623|

    High grade squamous intraepithelial lesion on cytologic smear of vagina (HGSIL)

  • R87.624|

    Cytologic evidence of malignancy on smear of vagina

  • R87.625|

    Unsatisfactory cytologic smear of vagina

  • R87.628|

    Other abnormal cytological findings on specimens from vagina

  • R87.629|

    Unspecified abnormal cytological findings in specimens from vagina

  • R87.69|

    Abnormal cytological findings in specimens from other female genital organs

  • R87.7|

    Abnormal histological findings in specimens from female genital organs

  • R87.8|

    Other abnormal findings in specimens from female genital organs

  • R87.81|

    High risk human papillomavirus (HPV) DNA test positive from female genital organs

  • R87.810|

    Cervical high risk human papillomavirus (HPV) DNA test positive

  • R87.811|

    Vaginal high risk human papillomavirus (HPV) DNA test positive

PreviousPage 17 of 20Next