Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R87.82|

    Low risk human papillomavirus (HPV) DNA test positive from female genital organs

  • R87.820|

    Cervical low risk human papillomavirus (HPV) DNA test positive

  • R87.821|

    Vaginal low risk human papillomavirus (HPV) DNA test positive

  • R87.89|

    Other abnormal findings in specimens from female genital organs

  • R87.9|

    Unspecified abnormal finding in specimens from female genital organs

  • R88|

    Abnormal findings in other body fluids and substances

  • R88.0|

    Cloudy (hemodialysis) (peritoneal) dialysis effluent

  • R88.8|

    Abnormal findings in other body fluids and substances

  • R89|

    Abnormal findings in specimens from other organs, systems and tissues

  • R89.0|

    Abnormal level of enzymes in specimens from other organs, systems and tissues

  • R89.1|

    Abnormal level of hormones in specimens from other organs, systems and tissues

  • R89.2|

    Abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues

  • R89.3|

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from other organs, systems and tissues

  • R89.4|

    Abnormal immunological findings in specimens from other organs, systems and tissues

  • R89.5|

    Abnormal microbiological findings in specimens from other organs, systems and tissues

  • R89.6|

    Abnormal cytological findings in specimens from other organs, systems and tissues

  • R89.7|

    Abnormal histological findings in specimens from other organs, systems and tissues

  • R89.8|

    Other abnormal findings in specimens from other organs, systems and tissues

  • R89.9|

    Unspecified abnormal finding in specimens from other organs, systems and tissues

  • R90|

    Abnormal findings on diagnostic imaging of central nervous system

  • R90.0|

    Intracranial space-occupying lesion found on diagnostic imaging of central nervous system

  • R90.8|

    Other abnormal findings on diagnostic imaging of central nervous system

  • R90.81|

    Abnormal echoencephalogram

  • R90.82|

    White matter disease, unspecified

  • R90.89|

    Other abnormal findings on diagnostic imaging of central nervous system

  • R91|

    Abnormal findings on diagnostic imaging of lung

  • R91.1|

    Solitary pulmonary nodule

  • R91.8|

    Other nonspecific abnormal finding of lung field

  • R92|

    Abnormal and inconclusive findings on diagnostic imaging of breast

  • R92.0|

    Mammographic microcalcification found on diagnostic imaging of breast

  • R92.1|

    Mammographic calcification found on diagnostic imaging of breast

  • R92.2|

    Inconclusive mammogram

  • R92.3|

    Mammographic density found on imaging of breast

  • R92.30|

    Dense breasts, unspecified

  • R92.31|

    Mammographic fatty tissue density of breast

  • R92.311|

    Mammographic fatty tissue density, right breast

  • R92.312|

    Mammographic fatty tissue density, left breast

  • R92.313|

    Mammographic fatty tissue density, bilateral breasts

  • R92.32|

    Mammographic fibroglandular density of breast

  • R92.321|

    Mammographic fibroglandular density, right breast

  • R92.322|

    Mammographic fibroglandular density, left breast

  • R92.323|

    Mammographic fibroglandular density, bilateral breasts

  • R92.33|

    Mammographic heterogeneous density of breast

  • R92.331|

    Mammographic heterogeneous density, right breast

  • R92.332|

    Mammographic heterogeneous density, left breast

  • R92.333|

    Mammographic heterogeneous density, bilateral breasts

  • R92.34|

    Mammographic extreme density of breast

  • R92.341|

    Mammographic extreme density, right breast

  • R92.342|

    Mammographic extreme density, left breast

  • R92.343|

    Mammographic extreme density, bilateral breasts

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