Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R82.89|

    Other abnormal findings on cytological and histological examination of urine

  • R82.9|

    Other and unspecified abnormal findings in urine

  • R82.90|

    Unspecified abnormal findings in urine

  • R82.91|

    Other chromoabnormalities of urine

  • R82.99|

    Other abnormal findings in urine

  • R82.991|

    Hypocitraturia

  • R82.992|

    Hyperoxaluria

  • R82.993|

    Hyperuricosuria

  • R82.994|

    Hypercalciuria

  • R82.998|

    Other abnormal findings in urine

  • R83|

    Abnormal findings in cerebrospinal fluid

  • R83.0|

    Abnormal level of enzymes in cerebrospinal fluid

  • R83.1|

    Abnormal level of hormones in cerebrospinal fluid

  • R83.2|

    Abnormal level of other drugs, medicaments and biological substances in cerebrospinal fluid

  • R83.3|

    Abnormal level of substances chiefly nonmedicinal as to source in cerebrospinal fluid

  • R83.4|

    Abnormal immunological findings in cerebrospinal fluid

  • R83.5|

    Abnormal microbiological findings in cerebrospinal fluid

  • R83.6|

    Abnormal cytological findings in cerebrospinal fluid

  • R83.8|

    Other abnormal findings in cerebrospinal fluid

  • R83.9|

    Unspecified abnormal finding in cerebrospinal fluid

  • R84|

    Abnormal findings in specimens from respiratory organs and thorax

  • R84.0|

    Abnormal level of enzymes in specimens from respiratory organs and thorax

  • R84.1|

    Abnormal level of hormones in specimens from respiratory organs and thorax

  • R84.2|

    Abnormal level of other drugs, medicaments and biological substances in specimens from respiratory organs and thorax

  • R84.3|

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from respiratory organs and thorax

  • R84.4|

    Abnormal immunological findings in specimens from respiratory organs and thorax

  • R84.5|

    Abnormal microbiological findings in specimens from respiratory organs and thorax

  • R84.6|

    Abnormal cytological findings in specimens from respiratory organs and thorax

  • R84.7|

    Abnormal histological findings in specimens from respiratory organs and thorax

  • R84.8|

    Other abnormal findings in specimens from respiratory organs and thorax

  • R84.9|

    Unspecified abnormal finding in specimens from respiratory organs and thorax

  • R85|

    Abnormal findings in specimens from digestive organs and abdominal cavity

  • R85.0|

    Abnormal level of enzymes in specimens from digestive organs and abdominal cavity

  • R85.1|

    Abnormal level of hormones in specimens from digestive organs and abdominal cavity

  • R85.2|

    Abnormal level of other drugs, medicaments and biological substances in specimens from digestive organs and abdominal cavity

  • R85.3|

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity

  • R85.4|

    Abnormal immunological findings in specimens from digestive organs and abdominal cavity

  • R85.5|

    Abnormal microbiological findings in specimens from digestive organs and abdominal cavity

  • R85.6|

    Abnormal cytological findings in specimens from digestive organs and abdominal cavity

  • R85.61|

    Abnormal cytologic smear of anus

  • R85.610|

    Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)

  • R85.611|

    Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H)

  • R85.612|

    Low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL)

  • R85.613|

    High grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL)

  • R85.614|

    Cytologic evidence of malignancy on smear of anus

  • R85.615|

    Unsatisfactory cytologic smear of anus

  • R85.616|

    Satisfactory anal smear but lacking transformation zone

  • R85.618|

    Other abnormal cytological findings on specimens from anus

  • R85.619|

    Unspecified abnormal cytological findings in specimens from anus

  • R85.69|

    Abnormal cytological findings in specimens from other digestive organs and abdominal cavity

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