Other disorders of pancreatic internal secretion
In Other disorders of glucose regulation and pancreatic internal secretion (E15-E16), chapter 4: Endocrine, Nutritional and Metabolic Diseases
10 billable codes under E16: none are a CC or MCC; none map to an HCC.
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Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Covers diabetes mellitus coding, including type, insulin and drug use, pump malfunction and secondary diabetes, plus obesity and obesity class codes.
- Diabetes mellitus (page 39)
- Obesity (page 42)
All codes under E16
E16 can't be used on a claim. Pick a billable code below; grey headings group them.
- E16.0Drug-induced hypoglycemia without coma
- E16.1Other hypoglycemia
- E16.2Hypoglycemia, unspecified
- E16.3Increased secretion of glucagon
- E16.4Increased secretion of gastrin
- E16.8Other specified disorders of pancreatic internal secretion
- E16.9Disorder of pancreatic internal secretion, unspecified
- E16.AHypoglycemia level
- E16.A1Hypoglycemia level 1
- E16.A2Hypoglycemia level 2
- E16.A3Hypoglycemia level 3
E16 MS-DRGs
As the principal diagnosis, the billable codes under E16 group to these 8 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 643 Endocrine Disorders with MCC (8 of 10 codes)
- DRG 644 Endocrine Disorders with CC (8 of 10 codes)
- DRG 645 Endocrine Disorders without CC/MCC (8 of 10 codes)
- DRG 380 Complicated Peptic Ulcer with MCC (1 of 10 codes)
- DRG 381 Complicated Peptic Ulcer with CC (1 of 10 codes)
- DRG 382 Complicated Peptic Ulcer without CC/MCC (1 of 10 codes)
- DRG 640 Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC (1 of 10 codes)
- DRG 641 Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC (1 of 10 codes)
Other codes that refer to E16
Notes on these codes point to E16.
- G63 Code First: endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Pancreatic Diseases
The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:
Read more about pancreatic diseases on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
