Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

All Codes Billable Only

Internal Codes

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D68.61|
Antiphospholipid syndrome
D68.62|
Lupus anticoagulant syndrome
D68.69|
Other thrombophilia
D68.8|
Other specified coagulation defects
D68.9|
Coagulation defect, unspecified
D69.0|
Allergic purpura
D69.1|
Qualitative platelet defects
D69.2|
Other nonthrombocytopenic purpura
D69.3|
Immune thrombocytopenic purpura
D69.41|
Evans syndrome
D69.42|
Congenital and hereditary thrombocytopenia purpura
D69.49|
Other primary thrombocytopenia
D69.51|
Posttransfusion purpura
D69.59|
Other secondary thrombocytopenia
D69.6|
Thrombocytopenia, unspecified
D69.8|
Other specified hemorrhagic conditions
D69.9|
Hemorrhagic condition, unspecified
D70.0|
Congenital agranulocytosis
D70.1|
Agranulocytosis secondary to cancer chemotherapy
D70.2|
Other drug-induced agranulocytosis
D70.3|
Neutropenia due to infection
D70.4|
Cyclic neutropenia
D70.8|
Other neutropenia
D70.9|
Neutropenia, unspecified
D71.1|
Leukocyte adhesion deficiency
D71.8|
Other functional disorders of polymorphonuclear neutrophils
D71.9|
Functional disorders of polymorphonuclear neutrophils, unspecified
D72.0|
Genetic anomalies of leukocytes
D72.10|
Eosinophilia, unspecified
D72.110|
Idiopathic hypereosinophilic syndrome [IHES]
D72.111|
Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
D72.118|
Other hypereosinophilic syndrome
D72.119|
Hypereosinophilic syndrome [HES], unspecified
D72.12|
Drug rash with eosinophilia and systemic symptoms syndrome
D72.18|
Eosinophilia in diseases classified elsewhere
D72.19|
Other eosinophilia
D72.810|
Lymphocytopenia
D72.818|
Other decreased white blood cell count
D72.819|
Decreased white blood cell count, unspecified
D72.820|
Lymphocytosis (symptomatic)
D72.821|
Monocytosis (symptomatic)
D72.822|
Plasmacytosis
D72.823|
Leukemoid reaction
D72.824|
Basophilia
D72.825|
Bandemia
D72.828|
Other elevated white blood cell count
D72.829|
Elevated white blood cell count, unspecified
D72.89|
Other specified disorders of white blood cells
D72.9|
Disorder of white blood cells, unspecified
D73.0|
Hyposplenism

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