All ICD10 Codes
Chapter 3

D50–D89: Diseases of the Blood and Blood-Forming Organs

Diseases of the Blood and Blood-Forming Organs diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
All CodesBillable Only
Internal Codes
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  • D57.411—

    Sickle-cell thalassemia, unspecified, with acute chest syndrome

  • D57.412—

    Sickle-cell thalassemia, unspecified, with splenic sequestration

  • D57.413—

    Sickle-cell thalassemia, unspecified, with cerebral vascular involvement

  • D57.414—

    Sickle-cell thalassemia, unspecified, with dactylitis

  • D57.418—

    Sickle-cell thalassemia, unspecified, with crisis with other specified complication

  • D57.419—

    Sickle-cell thalassemia, unspecified, with crisis

  • D57.42—

    Sickle-cell thalassemia beta zero without crisis

  • D57.431—

    Sickle-cell thalassemia beta zero with acute chest syndrome

  • D57.432—

    Sickle-cell thalassemia beta zero with splenic sequestration

  • D57.433—

    Sickle-cell thalassemia beta zero with cerebral vascular involvement

  • D57.434—

    Sickle-cell thalassemia beta zero with dactylitis

  • D57.438—

    Sickle-cell thalassemia beta zero with crisis with other specified complication

  • D57.439—

    Sickle-cell thalassemia beta zero with crisis, unspecified

  • D57.44—

    Sickle-cell thalassemia beta plus without crisis

  • D57.451—

    Sickle-cell thalassemia beta plus with acute chest syndrome

  • D57.452—

    Sickle-cell thalassemia beta plus with splenic sequestration

  • D57.453—

    Sickle-cell thalassemia beta plus with cerebral vascular involvement

  • D57.454—

    Sickle-cell thalassemia beta plus with dactylitis

  • D57.458—

    Sickle-cell thalassemia beta plus with crisis with other specified complication

  • D57.459—

    Sickle-cell thalassemia beta plus with crisis, unspecified

  • D57.80—

    Other sickle-cell disorders without crisis

  • D57.811—

    Other sickle-cell disorders with acute chest syndrome

  • D57.812—

    Other sickle-cell disorders with splenic sequestration

  • D57.813—

    Other sickle-cell disorders with cerebral vascular involvement

  • D57.814—

    Other sickle-cell disorders with dactylitis

  • D57.818—

    Other sickle-cell disorders with crisis with other specified complication

  • D57.819—

    Other sickle-cell disorders with crisis, unspecified

  • D58.0—

    Hereditary spherocytosis

  • D58.1—

    Hereditary elliptocytosis

  • D58.2—

    Other hemoglobinopathies

  • D58.8—

    Other specified hereditary hemolytic anemias

  • D58.9—

    Hereditary hemolytic anemia, unspecified

  • D59.0—

    Drug-induced autoimmune hemolytic anemia

  • D59.10—

    Autoimmune hemolytic anemia, unspecified

  • D59.11—

    Warm autoimmune hemolytic anemia

  • D59.12—

    Cold autoimmune hemolytic anemia

  • D59.13—

    Mixed type autoimmune hemolytic anemia

  • D59.19—

    Other autoimmune hemolytic anemia

  • D59.2—

    Drug-induced nonautoimmune hemolytic anemia

  • D59.30—

    Hemolytic-uremic syndrome, unspecified

  • D59.31—

    Infection-associated hemolytic-uremic syndrome

  • D59.32—

    Hereditary hemolytic-uremic syndrome

  • D59.39—

    Other hemolytic-uremic syndrome

  • D59.4—

    Other nonautoimmune hemolytic anemias

  • D59.5—

    Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

  • D59.6—

    Hemoglobinuria due to hemolysis from other external causes

  • D59.8—

    Other acquired hemolytic anemias

  • D59.9—

    Acquired hemolytic anemia, unspecified

  • D60.0—

    Chronic acquired pure red cell aplasia

  • D60.1—

    Transient acquired pure red cell aplasia

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