D84

Non-Billable
ChapterD50–D89
Rankcategory
Official Description

Other immunodeficiencies

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

D80-D89 Parent Instructions

Includes
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis
Excludes1(Not coded here)
  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)
  • human immunodeficiency virus [HIV] disease (B20)

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D80-D89Certain disorders involving the immune mechanism (D80-D89)
D84Other immunodeficiencies
D84.0Lymphocyte function antigen-1 [LFA-1] defect
D84.1Defects in the complement system
D84.8Other specified immunodeficiencies
D84.9Immunodeficiency, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D84:

blockD80-D89
Certain disorders involving the immune mechanism (D80-D89)
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D84. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Angioedema (allergic) (any site) (with urticaria)1 unique routes
hereditary→D84
Angioneurotic edema (allergic) (any site) (with urticaria)1 unique routes
hereditary→D84
Bannister's disease1 unique routes
hereditary→D84
Defect, defective2 unique routes
complement system→D84
lymphocyte function antigen-1 (LFA-1)→D84
Deficiency, deficient3 unique routes
C1 esterase inhibitor (C1-INH)→D84
immunity→D84(2 variants)
cell-mediated→D84
Edema, edematous (infectious) (pitting) (toxic)6 unique routes
angioneurotic (allergic) (any site) (with urticaria)
hereditary→D84
circumscribed, acute
hereditary→D84
essential, acute
hereditary→D84
glottis, glottic, glottidis (obstructive) (passive)
allergic
hereditary→D84
periodic
hereditary→D84
Quincke's
hereditary→D84
Giant1 unique routes
urticaria
hereditary→D84
Immunocompromised NOS1 unique routes
Direct index entry→D84
Immunodeficiency6 unique routes
Direct index entry→D84
due to(4 variants)
conditions classified elsewhere→D84
drugs→D84
external causes→D84
medication (current or past)→D84
specified type NEC→D84
Immunodeficient NOS1 unique routes
Direct index entry→D84
Immunosuppressed NOS1 unique routes
Direct index entry→D84
Quincke's disease or edema1 unique routes
hereditary→D84

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

Find Procedures (ICD-10-PCS)

Find surgical and procedural codes related to Other immunodeficiencies.

Search PCS Codes