D80-D89

Non-Billable
ChapterD50–D89
Rankblock
Official Description

Certain disorders involving the immune mechanism (D80-D89)

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Instructional Notes

Includes
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis
Excludes1(Not coded here)
  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)
  • human immunodeficiency virus [HIV] disease (B20)

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D80-D89Certain disorders involving the immune mechanism (D80-D89)
D80Immunodeficiency with predominantly antibody defects
D81Combined immunodeficiencies
D82Immunodeficiency associated with other major defects
D83Common variable immunodeficiency
D84Other immunodeficiencies
D86Sarcoidosis
D89Other disorders involving the immune mechanism, not elsewhere classified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D80-D89:

chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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