D57.00

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Hb-SS disease with crisis, unspecified

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Includes
  • Hb-SS disease with (painful) crisis NOS
  • Hb-SS disease with (vaso-occlusive) pain NOS
General instructions are available for the parent sections:
View CH3 NotesView D57 NotesView D57.0 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D57Sickle-cell disorders
D57.0Hb-SS disease with crisis
D57.00Hb-SS disease with crisis, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D57.00:

subcategoryD57.0
Hb-SS disease with crisis
View context instructions
categoryD57
Sickle-cell disorders
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D57.00. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

6 raw paths
Crisis2 unique routes
sickle-cell→D57.00(2 variants)
with
pain (vaso-occlusive)→D57.00
Disease, diseased4 unique routes
hemoglobin or Hb(2 variants)
S or SS(2 variants)
with(2 variants)
crisis (painful)→D57.00
pain (vaso-occlusive)→D57.00
sickle-cell(2 variants)
with(2 variants)
crisis (painful)→D57.00
pain (vaso-occlusive)→D57.00

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 811
Red Blood Cell Disorders with MCC
DRG 812
Red Blood Cell Disorders without MCC

Cross Reference

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