D53.0

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Protein deficiency anemia

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Includes
  • Amino-acid deficiency anemia
  • Orotaciduric anemia
Excludes1(Not coded here)
  • Lesch-Nyhan syndrome (E79.1)
General instructions are available for the parent sections:
View CH3 NotesView D53 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D50-D53Nutritional anemias (D50-D53)
D53Other nutritional anemias
D53.0Protein deficiency anemia

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D53.0:

categoryD53
Other nutritional anemias
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D53.0. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

12 raw paths
Aciduria1 unique routes
orotic (congenital) (hereditary) (pyrimidine deficiency)
anemia→D53.0
Amino-acid disorder1 unique routes
anemia→D53.0
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)8 unique routes
amino-acid-deficiency→D53.0
deficiency(2 variants)
amino-acid→D53.0
protein→D53.0
due to (in) (with)(2 variants)
deficiency(2 variants)
amino-acid→D53.0
protein→D53.0
megaloblastic
orotic aciduria→D53.0
orotaciduric (congenital) (hereditary)→D53.0
protein-deficiency→D53.0
Deficiency, deficient1 unique routes
protein
anemia→D53.0
Orotaciduria, oroticaciduria (congenital) (hereditary) (pyrimidine deficiency)1 unique routes
anemia→D53.0

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 811
Red Blood Cell Disorders with MCC
DRG 812
Red Blood Cell Disorders without MCC

Cross Reference

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