D53

Non-Billable
ChapterD50–D89
Rankcategory
Official Description

Other nutritional anemias

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Instructional Notes

Includes
  • megaloblastic anemia unresponsive to vitamin B12 or folate therapy

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D50-D53Nutritional anemias (D50-D53)
D53Other nutritional anemias
D53.0Protein deficiency anemia
D53.1Other megaloblastic anemias, not elsewhere classified
D53.2Scorbutic anemia
D53.8Other specified nutritional anemias
D53.9Nutritional anemia, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D53:

chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D53. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Aciduria1 unique routes
orotic (congenital) (hereditary) (pyrimidine deficiency)
anemia→D53
Amino-acid disorder1 unique routes
anemia→D53
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)23 unique routes
achrestic→D53
amino-acid-deficiency→D53
chronic
simple→D53
deficiency→D53(6 variants)
amino-acid→D53
combined B12 and folate→D53
nutritional→D53(2 variants)
with
specified deficiency NEC→D53
protein→D53
dimorphic→D53
diphasic→D53
due to (in) (with)(5 variants)
deficiency(5 variants)
amino-acid→D53
copper→D53
molybdenum→D53
protein→D53
zinc→D53
macrocytic→D53
malnutrition→D53
megaloblastic→D53(5 variants)
combined B12 and folate deficiency→D53
orotic aciduria→D53
refractory→D53
specified type NEC→D53

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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