D51.0

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Vitamin B12 deficiency anemia due to intrinsic factor deficiency

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Includes
  • Addison anemia
  • Biermer anemia
  • Pernicious (congenital) anemia
  • Congenital intrinsic factor deficiency
General instructions are available for the parent sections:
View CH3 NotesView D51 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D50-D53Nutritional anemias (D50-D53)
D51Vitamin B12 deficiency anemia
D51.0Vitamin B12 deficiency anemia due to intrinsic factor deficiency

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D51.0:

categoryD51
Vitamin B12 deficiency anemia
View context instructions
chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D51.0. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Addison-Biermer anemia (pernicious)1 unique routes
Direct index entry→D51.0
Addison's1 unique routes
anemia (pernicious)→D51.0
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)12 unique routes
Addison (-Biermer) (pernicious)→D51.0
Biermer's (pernicious)→D51.0
combined system disease NEC→D51.0
congenital
pernicious→D51.0
cytogenic→D51.0
deficiency(2 variants)
vitamin B12 NOS(2 variants)
due to
intrinsic factor deficiency→D51.0
pernicious→D51.0
malignant (progressive)→D51.0
pernicious (congenital) (malignant) (progressive)→D51.0
progressive(2 variants)
malignant→D51.0
pernicious→D51.0
vitamin
B12 deficiency (dietary) pernicious→D51.0
Biermer's (pernicious) anemia or disease1 unique routes
Direct index entry→D51.0
Congenital1 unique routes
intrinsic factor deficiency→D51.0
Deficiency, deficient1 unique routes
intrinsic
factor (congenital)→D51.0
Degeneration, degenerative1 unique routes
combined (spinal cord) (subacute)
with anemia (pernicious)→D51.0
Disease, diseased5 unique routes
Addison's anemia (pernicious)→D51.0
Biermer's (pernicious anemia)→D51.0
Lichtheim's (subacute combined sclerosis with pernicious anemia)→D51.0
Putnam's (subacute combined sclerosis with pernicious anemia)→D51.0
Runeberg's (progressive pernicious anemia)→D51.0
Glossitis (chronic superficial) (gangrenous) (Moeller's)1 unique routes
Hunter's→D51.0
Hunter's1 unique routes
glossitis→D51.0

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 811
Red Blood Cell Disorders with MCC
DRG 812
Red Blood Cell Disorders without MCC

Cross Reference

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