D51

Non-Billable
ChapterD50–D89
Rankcategory
Official Description

Vitamin B12 deficiency anemia

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

CH3 Parent Instructions

Excludes2(Not included here)
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Instructional Notes

Excludes2(Not included here)
  • deficiency of other B group vitamins (E53-)

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D50-D53Nutritional anemias (D50-D53)
D51Vitamin B12 deficiency anemia
D51.0Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
D51.2Transcobalamin II deficiency
D51.3Other dietary vitamin B12 deficiency anemia
D51.8Other vitamin B12 deficiency anemias
D51.9Vitamin B12 deficiency anemia, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D51:

chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D51. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Addison-Biermer anemia (pernicious)1 unique routes
Direct index entry→D51
Addison's1 unique routes
anemia (pernicious)→D51
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)23 unique routes
Addison (-Biermer) (pernicious)→D51
Biermer's (pernicious)→D51
combined system disease NEC→D51(2 variants)
due to dietary vitamin B12 deficiency→D51
congenital
pernicious→D51
cytogenic→D51
deficiency(7 variants)
transcobalamin II→D51
vitamin B12 NOS→D51(6 variants)
dietary→D51
due to(2 variants)
intrinsic factor deficiency→D51
selective vitamin B12 malabsorption with proteinuria→D51
pernicious→D51
specified type NEC→D51
due to (in) (with)(3 variants)
dietary vitamin B12 deficiency→D51
selective vitamin B12 malabsorption with proteinuria→D51
transcobalamin II deficiency→D51
malignant (progressive)→D51
megaloblastic
hereditary→D51
pernicious (congenital) (malignant) (progressive)→D51
progressive(2 variants)
malignant→D51
pernicious→D51
vegan→D51
vitamin
B12 deficiency (dietary) pernicious→D51

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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