C49.0

Billable

ChapterC00–D49

Ranksubcategory

Official Description

Malignant neoplasm of connective and soft tissue of head, face and neck

Metadata & Insights

•2026 ICD-10-CM Edition - Effective October 1, 2025.
•Billable/specific code (valid for reimbursement).
•Chapter 2: Neoplasms (C00-D49).

Instructional Notes

Includes

Malignant neoplasm of connective tissue of ear
Malignant neoplasm of connective tissue of eyelid

Excludes1(Not coded here)

connective tissue of orbit (C69.6-)

General instructions are available for the parent sections:

View C49 Notes

Clinical Hierarchy

CH2Neoplasms (C00-D49)

C45-C49Malignant neoplasms of mesothelial and soft tissue (C45-C49)

C49Malignant neoplasm of other connective and soft tissue

C49.0Malignant neoplasm of connective and soft tissue of head, face and neck

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to C49.0:

categoryC49

Malignant neoplasm of other connective and soft tissue

View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to C49.0. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths

Neoplasm, neoplastic25 unique routes

carotid (artery)→C49.0

cartilage (articular) (joint) NEC(4 variants)

auricular→C49.0

ear (external)→C49.0

eyelid→C49.0

pinna→C49.0

connective tissue NEC(16 variants)

auricle (ear)→C49.0

cervical region→C49.0

cheek→C49.0

chin→C49.0

ear (external)→C49.0

eyelid→C49.0

face→C49.0

forehead→C49.0

head→C49.0

neck→C49.0

pterygoid fossa→C49.0

scalp→C49.0

submental→C49.0

supraclavicular region→C49.0

temple→C49.0

temporal region→C49.0

ear (external)

cartilage→C49.0

eyelid (lower) (skin) (upper)

cartilage→C49.0

fossa (of)

pterygoid→C49.0

pterygoid fossa→C49.0

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 542

Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with MCC

DRG 543

Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CC

DRG 544

Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy without CC/MCC

Cross Reference

Find Procedures (ICD-10-PCS)

Find surgical and procedural codes related to Malignant neoplasm of connective and soft tissue of head, face and neck.

Search PCS Codes