MS-DRG 543Medical

Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CC

Major Diagnostic Category 08·Grouped by diagnosis·FY 2027

MS-DRG 543 is a Medical Medicare Severity Diagnosis Related Group under Major Diagnostic Category 08 (MDC 08) with a Complication or Comorbidity (CC). It maps to 279 ICD-10-CM diagnosis codes. For FY 2027 it carries a relative weight of 1.0060 with a geometric mean length of stay of 3.4 days and an arithmetic mean of 4.2 days. Hospitals use this grouping to determine reimbursement for inpatient stays under Medicare.

FY 2027 payment data

From Table 5 of the FY 2027 IPPS Final Rule (CMS).

Relative weight:: 1.0060 (payment multiplier vs. the average case (1.0))
Geometric mean stay:: 3.4 days (used for transfer payments)
Average stay:: 4.2 days (arithmetic mean)
Post-acute transfer policy:: Yes (early transfers can be paid less)

Same condition, other severity levels

CMS splits one condition into separate DRGs by how sick the patient is. With MCC pays more than with CC, which pays more than without CC/MCC.

DRG	Title	Relative weight	Mean stay
542	Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with MCC	1.7211	4.9 days
543	Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CC (this page)	1.0060	3.4 days
544	Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy without CC/MCC	0.7406	2.7 days

Diagnosis codes (279)

As the principal diagnosis, these ICD-10-CM codes can group to DRG 543. 100% of the codes listed are billable.