C45Not billable, use a more specific code below

Mesothelioma

In Malignant neoplasms of mesothelial and soft tissue (C45-C49), chapter 2: Neoplasms

5 billable codes under C45: 3 are a CC; all map to HCC 19 (Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

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Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Rules for coding benign and malignant neoplasms: using the Neoplasm Table, sequencing primary and secondary sites, treatment encounters, complications, and current cancer versus personal history.

Read Section I.C.2 (page 32), 12 more topics

All codes under C45

C45 can't be used on a claim. Pick a billable code below; grey headings group them.

C45 MS-DRGs

As the principal diagnosis, the billable codes under C45 group to these 17 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

Other codes that refer to C45

Notes on these codes point to C45.

  • C30-C39 Excludes1: mesothelioma (C45.-)
  • C38 Excludes1: mesothelioma (C45.-)
  • C48 Excludes1: mesothelioma (C45.-)
  • C49 Excludes2: mesothelioma (C45.-)
  • Z85.83 Includes: Conditions classifiable to C40-C41; C45-C49

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Mesothelioma

The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma, also known as malignant mesothelioma, is cancer of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs.

Read more about mesothelioma on MedlinePlus

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.